CAS 137551-38-3|Poricoic acid A(F)

Introduction：Basic information about CAS 137551-38-3|Poricoic acid A(F), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Poricoic acid A(F) BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Poricoic acid A(F)
CAS Number	137551-38-3	Molecular Weight	498.694
Density	1.1±0.1 g/cm3	Boiling Point	664.0±55.0 °C at 760 mmHg
Molecular Formula	C₃₁H₄₆O₅	Melting Point	/
MSDS	/	Flash Point	369.3±28.0 °C

Names

Name	poricoic acid A
Synonym	More Synonyms

Poricoic acid A(F) BiologicalActivity

Description	Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity[1]. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis[2].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Dong H, et al. Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci. 2015 Jun;38(11):1977-82. [2]. Chen DQ, et al. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Free Radic Biol Med. 2019 Apr;134:484-497.

Description

Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity[1]. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis[2].

Related Catalog

Research Areas >>CancerSignaling Pathways >>Others >>Others

References

[1]. Dong H, et al. Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci. 2015 Jun;38(11):1977-82.

[2]. Chen DQ, et al. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Free Radic Biol Med. 2019 Apr;134:484-497.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	664.0±55.0 °C at 760 mmHg
Molecular Formula	C₃₁H₄₆O₅
Molecular Weight	498.694
Flash Point	369.3±28.0 °C
Exact Mass	498.334534
PSA	94.83000
LogP	7.26
Vapour Pressure	0.0±4.6 mmHg at 25°C
Index of Refraction	1.554
InChIKey	KVAQLXUMUVEKGR-SMFZDKLCSA-N
SMILES	C=C(CCC(C(=O)O)C1C(O)CC2(C)C3=CCC(C(=C)C)C(C)(CCC(=O)O)C3=CCC12C)C(C)C

Synonyms

(2R)-2-[(2R,3R,3aR,6S,7S,9bR)-6-(2-Carboxyethyl)-2-hydroxy-7-isopropenyl-3a,6,9b-trimethyl-2,3,3a,4,6,7,8,9b-octahydro-1H-cyclopenta[a]naphthalen-3-yl]-6-methyl-5-methyleneheptanoic acid

1H-Benz[e]indene-6-propanoic acid, 3-[(1R)-1-carboxy-5-methyl-4-methylenehexyl]-2,3,3a,4,6,7,8,9b-octahydro-2-hydroxy-3a,6,9b-trimethyl-7-(1-methylethenyl)-, (2R,3R,3aR,6S,7S,9bR)-

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