Introduction：Basic information about CAS 1350920-22-7|T.cruzi-IN-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | T.cruzi-IN-1 |
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| CAS Number | 1350920-22-7 | Molecular Weight | 390.44200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H25F3N2O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide |
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T.cruzi-IN-1 BiologicalActivity
| Description | T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1]. |
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| Related Catalog | Research Areas >>Infection |
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| Target | IC50: 8 nM (Trypanosoma cruzi)[1] |
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| In Vitro | T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity[1]. |
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| References | [1]. Germain AR, et al. Identification of small-molecule inhibitors of Trypansoma cruzi replication. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7197-200. |
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Chemical & Physical Properties
| Molecular Formula | C22H25F3N2O |
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| Molecular Weight | 390.44200 |
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| Exact Mass | 390.19200 |
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| PSA | 23.55000 |
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| LogP | 4.51390 |
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| Storage condition | -20℃ |
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