CAS 25695-95-8|(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol

Introduction：Basic information about CAS 25695-95-8|(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (2S,3S,4E)-2-Amino-4-octadecene-1,3-diol BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol
CAS Number	25695-95-8	Molecular Weight	299.492
Density	0.9±0.1 g/cm3	Boiling Point	445.9±45.0 °C at 760 mmHg
Molecular Formula	C₁₈H₃₇NO₂	Melting Point	/
MSDS	/	Flash Point	223.5±28.7 °C

Names

Name	(2S,3S,4E)-L-threo sphingosine
Synonym	More Synonyms

(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol BiologicalActivity

Description	L-threo-Sphingosine is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect[1].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerSignaling Pathways >>MAPK/ERK Pathway >>p38 MAPK
References	[1]. Sakakura C, et al. Selectivity of sphingosine-induced apoptosis. Lack of activity of DL-erythyro-dihydrosphingosine. Biochem Biophys Res Commun. 1998 May 29;246(3):827-30.

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	445.9±45.0 °C at 760 mmHg
Molecular Formula	C₁₈H₃₇NO₂
Molecular Weight	299.492
Flash Point	223.5±28.7 °C
Exact Mass	299.282440
PSA	66.48000
LogP	6.40
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.489
InChIKey	WWUZIQQURGPMPG-DNWQSSKHSA-N
SMILES	CCCCCCCCCCCCCC=CC(O)C(N)CO

Synonyms

(2S,3S,4E)-2-Amino-octadec-4-ene-1,3-diol

L-(-)-Threosphingenine

(2S,3S,4E)-L-threo-sphingosine

L-threo-sphingosine

4-Octadecene-1,3-diol, 2-amino-, (2S,3S,4E)-

(-)-(E,2S,3S)-2-aminooctadec-4-ene-1,3-diol

(2S,3S,4E)-2-Amino-4-octadecene-1,3-diol

(E)-(2S,3S)-2-Amino-octadec-4-ene-1,3-diol

(2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol

Recommended......