CAS 164332-88-1|N-Boc-PEG2-bromide

Introduction:Basic information about CAS 164332-88-1|N-Boc-PEG2-bromide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-Boc-PEG2-bromide
CAS Number164332-88-1Molecular Weight268.14800
Density/Boiling Point/
Molecular FormulaC9H18BrNO3Melting Point/
MSDS/Flash Point/

Names

Nametert-butyl [2-(2-bromoethoxy)ethyl]carbamate
SynonymMore Synonyms

N-Boc-PEG2-bromide BiologicalActivity

DescriptionN-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Ruben HERRENDORFF, et al. Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids. WO2017046172A1.

Chemical & Physical Properties

Molecular FormulaC9H18BrNO3
Molecular Weight268.14800
Exact Mass267.04700
PSA47.56000
LogP2.31350
InChIKeyDMOPZPBTLCZSGL-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)NCCOCCBr

Synonyms

tert-butyl 2-(2-bromoethoxy)ethylcarbamate
tert-butyl (2-(2-bromo)ethoxy)ethylcarbamate
[2-(2-Bromoethoxy)ethyl]carbamic acid 1,1-dimethylethyl ester
t-boc-N-amido-PEG2-bromide
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