CAS 1337482-15-1|N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl

Introduction:Basic information about CAS 1337482-15-1|N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl]-L-alanine 1-methylethyl ester
CAS Number1337482-15-1Molecular Weight529.453
Density1.4±0.1 g/cm3Boiling Point/
Molecular FormulaC22H29FN3O9PMelting Point/
MSDS/Flash Point/

Names

NameIsopropyl (2S)-2-{[{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydro-3-furanyl]oxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)
SynonymMore Synonyms

BiologicalActivity

DescriptionSofosbuvir impurity G, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
Related CatalogSignaling Pathways >>Anti-infection >>HCVResearch Areas >>Infection
Target

HCV[1]

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Molecular FormulaC22H29FN3O9P
Molecular Weight529.453
Exact Mass529.162537
LogP1.79
Index of Refraction1.573
InChIKeyIBMLPFZASPUMOW-UHFFFAOYSA-N
SMILESCC(C)OC(=O)C(C)NP(=O)(Oc1ccccc1)OC1C(CO)OC(n2ccc(=O)[nH]c2=O)C1(C)F
Storage condition2-8℃

Synonyms

Uridine, 2'-deoxy-2'-fluoro-2'-methyl-3'-O-[[[(1S)-1-methyl-2-(1-methylethoxy)-2-oxoethyl]amino]phenoxyphosphinyl]-
Isopropyl (2S)-2-{[{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydro-3-furanyl]oxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)
N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl]-L-alanine 1-methylethyl ester
Sofosbuvir impurity G
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