Introduction：Basic information about CAS 160896-49-1|Hosenkoside K, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hosenkoside K |
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| CAS Number | 160896-49-1 | Molecular Weight | 1141.293 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C54H92O25 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Hosenkoside K |
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| Synonym | More Synonyms |
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Hosenkoside K BiologicalActivity
| Description | Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyNatural Products >>Saccharides and Glycosides |
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| In Vivo | The mean peak concentrations of hosenkoside K in rats after oral administration of total saponins of Semen Impatientis is 511.11±234.07 ng/mL, occurring at times of 0.46 h. The terminal half-lives of hosenkoside A is 4.96±1.75 h[1]. |
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| Animal Admin | Male Wistar rats (7 weeks old, 220±20 g, n=6) are fasted for 12 h. Total saponins of Semen Impatientis at a dose of 300 mg (in 10 mL)/kg are orally administered to rats using a gastric gavage tube. The doses of hosenkoside A is12.4 mg/kg for an oral dose of 300 mg/kg total saponins. Blood samples (0.20 mL) are collected from suborbital vein into heparinized tubes before administration (0 min), and 0.08, 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 12 and 24 h after dosing. |
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| References | [1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3). |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Molecular Formula | C54H92O25 |
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| Molecular Weight | 1141.293 |
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| Exact Mass | 1140.592773 |
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| LogP | -1.90 |
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| Index of Refraction | 1.639 |
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| InChIKey | JWINIHBXRZXFKL-SGBJXWCQSA-N |
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| SMILES | CC(COC1OC(CO)C(O)C(O)C1O)C1CCC2(CCC3(C)C(CCC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6OC6OC(CO)C(O)C(O)C6O)C(C)(COC6OC(CO)C(O)C(O)C6O)C5CCC43C)C2O)CO1 |
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Synonyms
| Glucopyranoside |
| β-D-Glucopyranoside, (1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-glucopyranosyloxy)methyl]-6'-[(1S)-2-(β-D-glucopyranosyloxy)-1-methylethyl]octadecahydro-1-hydroxy-4a,4b,7,10a-tetram ethylspiro[chrysene-2(1H),3'(4'H)-[2H]pyran]-8-yl 2-O-β-D-glucopyranosyl- |
| (1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-Glucopyranosyloxy)methyl]-6'-[(2S)-1-(β-D-glucopyranosyloxy)-2-propanyl]-1-hydroxy-4a,4b,7,10a-tetramethyloctadecahydro-1H,4'H-spiro[chrysene -2,3'-pyran]-8-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside |
