CAS 1326-12-1|Thioflavine S
| Common Name | Thioflavine S | ||
|---|---|---|---|
| CAS Number | 1326-12-1 | Molecular Weight | 318.864 |
| Density | / | Boiling Point | / |
| Molecular Formula | C17H19ClN2S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | thioflavin T |
|---|---|
| Synonym | More Synonyms |
Thioflavine S BiologicalActivity
| Description | Thioflavine S is a fluorescent histochemical marker of dense core senile plaques. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersDye ReagentsResearch Areas >>Others |
| References | [1]. McLellan ME, et al. In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J Neurosci. 2003 Mar 15;23(6):2212-7. |
Chemical & Physical Properties
| Molecular Formula | C17H19ClN2S |
|---|---|
| Molecular Weight | 318.864 |
| Exact Mass | 318.095734 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
Articles37
More Articles| Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties. Bioorg. Med. Chem. 22(19) , 5298-307, (2014) Multitarget compounds are increasingly being pursued for the effective treatment of complex diseases. Herein, we describe the design and synthesis of a novel class of shogaol-huprine hybrids, purporte... | |
| β-cyclodextrin and curcumin, a potent cocktail for disaggregating and/or inhibiting amyloids: a case study with α-synuclein. Biochemistry 53(25) , 4081-3, (2014) Aggregation of α-synuclein has been implicated in Parkinson's disease (PD). While many compounds are known to inhibit α-synuclein aggregation, dissolution of aggregates into their constituent monomers... | |
| Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Nat. Commun. 6 , 6176, (2015) In Alzheimer's disease (AD), β-amyloid (Aβ) plaques are tightly enveloped by microglia processes, but the significance of this phenomenon is unknown. Here we show that microglia constitute a barrier w... |
Synonyms
| 2-[4-(Dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride |
| Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (1:1) |
| MFCD00071453 |
| EINECS 215-418-0 |
| Benzothiazolium, 2-[4- (dimethylamino)phenyl]-3,6-dimethyl-, chloride |
| thioflavin T |
| Thioflavine S |
