Introduction：Basic information about CAS 160498-02-2|Bisandrographolide C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bisandrographolide C |
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| CAS Number | 160498-02-2 | Molecular Weight | 664.868 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 832.6±65.0 °C at 760 mmHg |
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| Molecular Formula | C40H56O8 | Melting Point | / |
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| MSDS | / | Flash Point | 252.3±27.8 °C |
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Names
| Name | 5-{2-[(1R,4aS,5R,6R,8aS)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]-1-(2-oxo-2,5-dihydro-3-furanyl)ethyl}-3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone |
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| Synonym | More Synonyms |
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Bisandrographolide C BiologicalActivity
| Description | Bisandrographolide C is an unusual dimer of ent-labdane diterpenoid isolated and identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels with Kd values of 289 and 341 μM respectively, and protects cardiomyocytes from hypoxia-reoxygenation injury[1]. |
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| Related Catalog | Research Areas >>Others |
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| References | [1]. Gao S, et al. Unusual ent-Labdane Diterpenoid Dimers and their Selective Activation of TRPV Channels. J Org Chem. 2019 Nov 1;84(21):13595-13603. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 832.6±65.0 °C at 760 mmHg |
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| Molecular Formula | C40H56O8 |
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| Molecular Weight | 664.868 |
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| Flash Point | 252.3±27.8 °C |
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| Exact Mass | 664.397522 |
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| LogP | 3.82 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.596 |
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| InChIKey | WQHWOZANSOUSAY-MDZDMXLPSA-N |
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| SMILES | C=C1CCC2C(C)(CO)C(O)CCC2(C)C1C=CC1=CC(C(CC2C(=C)CCC3C(C)(CO)C(O)CCC23C)C2=CCOC2=O)OC1=O |
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| Storage condition | 2-8℃ |
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Synonyms
| 2(5H)-Furanone, 5-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]-1-(2,5-dihydro-2-oxo-3-furanyl)ethyl]-3-[(E)-2-[(1R,4aS,5R,6R,8aR)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethenyl]- |
| 5-{2-[(1R,4aS,5R,6R,8aS)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]-1-(2-oxo-2,5-dihydro-3-furanyl)ethyl}-3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone |
