Introduction：Basic information about CAS 1359825-94-7|RTC13, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | RTC13 |
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| CAS Number | 1359825-94-7 | Molecular Weight | 315.30 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C14H9N3O4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | RTC13 |
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| Synonym | More Synonyms |
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RTC13 BiologicalActivity
| Description | RTC13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy (DMD)[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| In Vivo | Animal Model: Wild-type (C57BL/10) mice at 10 to 12 weeks of age[1]. Dosage: 10 (n = 5), 30 (n = 5), 60 (n = 5) or 300 mg/kg (n = 5). Administration: Intraperitoneal Administration. Result: No changes were observed in liver and kidney weights at the time of necropsies, and Hematoxylin and Eosin (H&E) staining revealed the absence of histopathological changes. |
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| References | [1]. Refik Kayali, et al. Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy. Hum Mol Genet. 2012 Sep 15;21(18):4007-20. |
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Chemical & Physical Properties
| Molecular Formula | C14H9N3O4S |
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| Molecular Weight | 315.30 |
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| Exact Mass | 315.03100 |
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| PSA | 139.71000 |
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| LogP | 3.44290 |
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Synonyms
| (5Z)-2-Amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-4(5H)-thiazolone |
| (Z)-2-amino-5-((5-(2-nitrophenyl)furan-2-yl)methylene)thiazol-4(5H)-one |
| 4(5H)-Thiazolone, 2-amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-, (5Z)- |
