Introduction：Basic information about CAS 1371587-51-7|Cavosonstat, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cavosonstat |
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| CAS Number | 1371587-51-7 | Molecular Weight | 299.708 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 527.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H10ClNO3 | Melting Point | / |
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| MSDS | / | Flash Point | 272.8±30.1 °C |
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Names
| Name | Cavosonstat |
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| Synonym | More Synonyms |
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Cavosonstat BiologicalActivity
| Description | Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>CFTRSignaling Pathways >>Metabolic Enzyme/Protease >>GSNORResearch Areas >>Inflammation/Immunology |
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| In Vitro | Cavosonstat (N91115), a CFTR modulator, promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stability, with a mechanism of action complementary to CFTR correctors and potentiators[1]. |
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| References | [1]. Scott H Donaldson, et al. Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May;16(3):371-379. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 527.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C16H10ClNO3 |
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| Molecular Weight | 299.708 |
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| Flash Point | 272.8±30.1 °C |
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| Exact Mass | 299.034912 |
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| LogP | 4.28 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.715 |
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Synonyms
| 3-Chloro-4-(6-hydroxy-2-quinolinyl)benzoic acid |
| O2Z8Q22ZE4 |
| UNII:O2Z8Q22ZE4 |
| Cavosonstat |
| 10452 |
| N91115 |
| Benzoic acid, 3-chloro-4-(6-hydroxy-2-quinolinyl)- |
