Introduction：Basic information about CAS 1309666-78-1|Tos-PEG2-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tos-PEG2-Boc |
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| CAS Number | 1309666-78-1 | Molecular Weight | 344.423 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 460.6±30.0 °C at 760 mmHg |
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| Molecular Formula | C16H24O6S | Melting Point | / |
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| MSDS | / | Flash Point | 232.3±24.6 °C |
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Names
| Name | Tos-PEG2-t-butyl ester |
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| Synonym | More Synonyms |
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Tos-PEG2-Boc BiologicalActivity
| Description | Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 460.6±30.0 °C at 760 mmHg |
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| Molecular Formula | C16H24O6S |
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| Molecular Weight | 344.423 |
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| Flash Point | 232.3±24.6 °C |
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| Exact Mass | 344.129364 |
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| LogP | 2.81 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.501 |
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| InChIKey | OVLSSENVXOKYAD-UHFFFAOYSA-N |
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| SMILES | Cc1ccc(S(=O)(=O)OCCOCCC(=O)OC(C)(C)C)cc1 |
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Safety Information
Synonyms
| Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester |
| MFCD22201525 |
| 2-Methyl-2-propanyl 3-(2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)propanoate |
