Introduction：Basic information about CAS 132152-57-9|Epi-Cryptoacetalide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Epi-Cryptoacetalide |
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| CAS Number | 132152-57-9 | Molecular Weight | 286.366 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 464.9±45.0 °C at 760 mmHg |
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| Molecular Formula | C18H22O3 | Melting Point | / |
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| MSDS | / | Flash Point | 199.8±23.3 °C |
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Names
| Name | Epi-Cryptoacetalide |
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| Synonym | More Synonyms |
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Epi-Cryptoacetalide BiologicalActivity
| Description | Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with Ki values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities[1]. |
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| Related Catalog | Signaling Pathways >>Others >>Estrogen Receptor/ERRResearch Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Prostaglandin ReceptorResearch Areas >>Inflammation/Immunology |
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| Target | Ki: 0.3 μM (ER-α) and 1.92 μM (EP2 subtype)[1] |
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| In Vitro | Epi-cryptoacetalide 是丹参中的一种成分，具有散瘀止痛、活血通经、除烦等功效； 月经不调，经闭，痛经，脘腹作痛，胸腹刺痛，热痹，疮疡疮毒，失眠，肝脾肿痛，心绞痛。 |
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| References | [1]. Herbert Situmorang, et al. IN-SILICO dynamic analysis of Sulawesi propolis as anti-endometriosis drug: Interaction study with TNF alpha receptor, NF-kB, estrogen receptor, progesterone receptor and prostaglandin receptor. Ann Med Surg (Lond). 2021 Jun 17;67:102459. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 464.9±45.0 °C at 760 mmHg |
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| Molecular Formula | C18H22O3 |
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| Molecular Weight | 286.366 |
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| Flash Point | 199.8±23.3 °C |
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| Exact Mass | 286.156891 |
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| LogP | 4.39 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.580 |
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| InChIKey | HUTQFIYQAWCICW-BBATYDOGSA-N |
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| SMILES | CC1COC2(C1)OC(=O)c1c2ccc2c1CCCC2(C)C |
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Synonyms
| Spiro[furan-2(3H),3'(1'H)-naphtho[1,2-c]furan]-1'-one, 4,5,6',7',8',9'-hexahydro-4,6',6'-trimethyl-, (2R,4R)- |
| (2R,4R)-4,6',6'-Trimethyl-4,5,6',7',8',9'-hexahydro-1'H,3H-spiro[furan-2,3'-naphtho[1,2-c]furan]-1'-one |
