CAS 1346502-15-5|Br-PEG3-CH2COOH

Introduction:Basic information about CAS 1346502-15-5|Br-PEG3-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBr-PEG3-CH2COOH
CAS Number1346502-15-5Molecular Weight/
Density/Boiling Point/
Molecular Formula/Melting Point/
MSDS/Flash Point/

Names

NameBr-PEG3-CH2CO2H

Br-PEG3-CH2COOH BiologicalActivity

DescriptionBr-PEG3-CH2COOH (compound 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Zha Z, et al. Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA). J Med Chem. 2011 Dec 8;54(23):8085-98.

Chemical & Physical Properties

No Any Chemical & Physical Properties
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