Introduction：Basic information about CAS 1351556-81-4|Propargyl-PEG8-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propargyl-PEG8-OH |
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| CAS Number | 1351556-81-4 | Molecular Weight | 408.484 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 483.5±40.0 °C at 760 mmHg |
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| Molecular Formula | C19H36O9 | Melting Point | / |
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| MSDS | / | Flash Point | 246.2±27.3 °C |
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Names
| Name | Propargyl-PEG9-alcohol |
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| Synonym | More Synonyms |
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Propargyl-PEG8-OH BiologicalActivity
| Description | Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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| References | [1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 483.5±40.0 °C at 760 mmHg |
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| Molecular Formula | C19H36O9 |
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| Molecular Weight | 408.484 |
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| Flash Point | 246.2±27.3 °C |
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| Exact Mass | 408.235931 |
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| LogP | -2.76 |
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| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
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| Index of Refraction | 1.465 |
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| InChIKey | SDOHHKOXBMTMMG-UHFFFAOYSA-N |
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| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCCOCCO |
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Synonyms
| MFCD27635157 |
| 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-ol |
