Introduction：Basic information about CAS 1374658-85-1|Azido-PEG1-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG1-Boc |
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| CAS Number | 1374658-85-1 | Molecular Weight | 215.250 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C9H17N3O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Azido-PEG1-t-butyl ester |
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| Synonym | More Synonyms |
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Azido-PEG1-Boc BiologicalActivity
| Description | Azido-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C9H17N3O3 |
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| Molecular Weight | 215.250 |
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| Exact Mass | 215.126984 |
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| LogP | 1.70 |
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| InChIKey | YQLWGRGAPJGNNQ-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)CCOCCN=[N+]=[N-] |
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Synonyms
| MFCD22201524 |
| Propanoic acid, 3-(2-azidoethoxy)-, 1,1-dimethylethyl ester |
| 2-Methyl-2-propanyl 3-(2-azidoethoxy)propanoate |
