Introduction：Basic information about CAS 1381861-91-1|Bromo-PEG2-C2-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromo-PEG2-C2-Boc |
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| CAS Number | 1381861-91-1 | Molecular Weight | 297.18604 |
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| Density | 1.240±0.06 g/cm3 | Boiling Point | 332.0±22.0 °C |
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| Molecular Formula | C11H21BrO4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Bromo-PEG2-t-butyl ester |
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| Synonym | More Synonyms |
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Bromo-PEG2-C2-Boc BiologicalActivity
| Description | Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.240±0.06 g/cm3 |
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| Boiling Point | 332.0±22.0 °C |
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| Molecular Formula | C11H21BrO4 |
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| Molecular Weight | 297.18604 |
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| InChIKey | UOYAYHGUAATLSG-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)CCOCCOCCBr |
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Synonyms
