Introduction：Basic information about CAS 1623792-00-6|Bromo-PEG8-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromo-PEG8-Boc |
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| CAS Number | 1623792-00-6 | Molecular Weight | 561.501 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 557.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C23H45BrO10 | Melting Point | / |
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| MSDS | / | Flash Point | 290.6±28.7 °C |
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Names
| Name | Bromo-PEG8-t-butyl ester |
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| Synonym | More Synonyms |
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Bromo-PEG8-Boc BiologicalActivity
| Description | Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 557.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C23H45BrO10 |
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| Molecular Weight | 561.501 |
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| Flash Point | 290.6±28.7 °C |
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| Exact Mass | 560.219604 |
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| LogP | -0.11 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.467 |
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| InChIKey | DXYYTZDPNRZUDL-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCBr |
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Synonyms
| 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-bromo-, 1,1-dimethylethyl ester |
| MFCD26793748 |
| 2-Methyl-2-propanyl 1-bromo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate |
