Introduction：Basic information about CAS 1818294-29-9|Propargyl-PEG7-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propargyl-PEG7-Boc |
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| CAS Number | 1818294-29-9 | Molecular Weight | 448.548 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 494.3±40.0 °C at 760 mmHg |
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| Molecular Formula | C22H40O9 | Melting Point | / |
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| MSDS | / | Flash Point | 207.8±27.4 °C |
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Names
| Name | Propargyl-PEG7-t-butyl ester |
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| Synonym | More Synonyms |
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Propargyl-PEG7-Boc BiologicalActivity
| Description | Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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| References | [1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 494.3±40.0 °C at 760 mmHg |
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| Molecular Formula | C22H40O9 |
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| Molecular Weight | 448.548 |
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| Flash Point | 207.8±27.4 °C |
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| Exact Mass | 448.267242 |
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| LogP | -0.18 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.459 |
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| InChIKey | ZYHHJKFUMHBJSI-UHFFFAOYSA-N |
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| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C |
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Synonyms
| 2-Methyl-2-propanyl 4,7,10,13,16,19,22-heptaoxapentacos-24-yn-1-oate |
| 4,7,10,13,16,19,22-Heptaoxapentacos-24-yn-1-oic acid, 1,1-dimethylethyl ester |
| MFCD22683299 |
