CAS 1818294-43-7|Azido-PEG9-Boc
Introduction：Basic information about CAS 1818294-43-7|Azido-PEG9-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG9-Boc | ||
|---|---|---|---|
| CAS Number | 1818294-43-7 | Molecular Weight | 567.67 |
| Density | / | Boiling Point | / |
| Molecular Formula | C25H49N3O11 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | Azido-PEG9-t-butyl ester |
|---|
Azido-PEG9-Boc BiologicalActivity
| Description | Azido-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
| Target | PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
Chemical & Physical Properties
| Molecular Formula | C25H49N3O11 |
|---|---|
| Molecular Weight | 567.67 |
| InChIKey | HNZVYHQBKFTIJZ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
