CAS 1818294-46-0|Mal-PEG8-acid

Introduction:Basic information about CAS 1818294-46-0|Mal-PEG8-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMal-PEG8-acid
CAS Number1818294-46-0Molecular Weight521.555
Density1.2±0.1 g/cm3Boiling Point634.6±55.0 °C at 760 mmHg
Molecular FormulaC23H39NO12Melting Point/
MSDS/Flash Point337.6±31.5 °C

Names

NameMal-PEG8-acid
SynonymMore Synonyms

Mal-PEG8-acid BiologicalActivity

DescriptionMal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point634.6±55.0 °C at 760 mmHg
Molecular FormulaC23H39NO12
Molecular Weight521.555
Flash Point337.6±31.5 °C
Exact Mass521.247253
LogP-2.88
Vapour Pressure0.0±4.0 mmHg at 25°C
Index of Refraction1.496
InChIKeyKLZPPWOSICDUKQ-UHFFFAOYSA-N
SMILESO=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O

Synonyms

MFCD26793771
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid
3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
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