Introduction:Basic information about CAS 1818294-46-0|Mal-PEG8-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Mal-PEG8-acid |
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| CAS Number | 1818294-46-0 | Molecular Weight | 521.555 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 634.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C23H39NO12 | Melting Point | / |
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| MSDS | / | Flash Point | 337.6±31.5 °C |
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Names
| Name | Mal-PEG8-acid |
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| Synonym | More Synonyms |
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Mal-PEG8-acid BiologicalActivity
| Description | Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 634.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C23H39NO12 |
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| Molecular Weight | 521.555 |
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| Flash Point | 337.6±31.5 °C |
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| Exact Mass | 521.247253 |
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| LogP | -2.88 |
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| Vapour Pressure | 0.0±4.0 mmHg at 25°C |
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| Index of Refraction | 1.496 |
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| InChIKey | KLZPPWOSICDUKQ-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O |
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Synonyms
| MFCD26793771 |
| 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid |
| 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)- |