Introduction：Basic information about CAS 251647-53-7|2'-O-MOE-A(Bz)-3'-phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-O-MOE-A(Bz)-3'-phosphoramidite |
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| CAS Number | 251647-53-7 | Molecular Weight | 917.98 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C49H56N7O9P | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2'-O-MOE-A(Bz)-3'-phosphoramidite |
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| Synonym | More Synonyms |
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2'-O-MOE-A(Bz)-3'-phosphoramidite BiologicalActivity
| Description | DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. |
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Chemical & Physical Properties
| Molecular Formula | C49H56N7O9P |
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| Molecular Weight | 917.98 |
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| Exact Mass | 931.403381 |
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| LogP | 10.19 |
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| InChIKey | VPBYBQBHLYRLHG-UHFFFAOYSA-N |
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| SMILES | COCCOC1C(OP(OCCC#N)N(C(C)C)C(C)C)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC1n1cnc2c(NC(=O)c3ccccc3)ncnc21 |
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| Storage condition | 2-8℃ |
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Synonyms
| N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)adenosine |
| Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-O-(2-methoxyethyl)- |
