Introduction：Basic information about CAS 1351373-47-1|Bis-propargyl-PEG9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bis-propargyl-PEG9 |
|---|
| CAS Number | 1351373-47-1 | Molecular Weight | 490.584 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 529.5±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C24H42O10 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 197.4±28.6 °C |
|---|
Names
| Name | Bis-Propargyl-PEG10 |
|---|
| Synonym | More Synonyms |
|---|
Bis-propargyl-PEG9 BiologicalActivity
| Description | Bis-propargyl-PEG9 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG9 can be used to synthesize the bivalent estrogen receptor ligands[1]. |
|---|
| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
|---|
| References | [1]. Shan M, et al. Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding. Chembiochem. 2011 Nov 25;12(17):2587-98. |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 529.5±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C24H42O10 |
|---|
| Molecular Weight | 490.584 |
|---|
| Flash Point | 197.4±28.6 °C |
|---|
| Exact Mass | 490.277802 |
|---|
| LogP | -2.20 |
|---|
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.466 |
|---|
| InChIKey | LGMGZRHYRPWDIM-UHFFFAOYSA-N |
|---|
| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C |
|---|
| Storage condition | 2-8°C |
|---|
Synonyms
| MFCD28976686 |
| 4,7,10,13,16,19,22,25,28,31-Decaoxatetratriaconta-1,33-diyne |
