CAS 1623791-99-0|Azido-PEG8-Boc

Introduction:Basic information about CAS 1623791-99-0|Azido-PEG8-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAzido-PEG8-Boc
CAS Number1623791-99-0Molecular Weight523.62
Density/Boiling Point/
Molecular FormulaC23H45N3O10Melting Point/
MSDS/Flash Point/

Names

NameAzido-PEG8-t-butyl ester

Azido-PEG8-Boc BiologicalActivity

DescriptionAzido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

Alkyl/ether

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239.

Chemical & Physical Properties

Molecular FormulaC23H45N3O10
Molecular Weight523.62
InChIKeyLBNCLZBCQUTBAP-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
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