Introduction：Basic information about CAS 1638497-26-3|R-Avanafil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | R-Avanafil |
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| CAS Number | 1638497-26-3 | Molecular Weight | / |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C23H26ClN7O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
R-Avanafil BiologicalActivity
| Description | (R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC50: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction[1]. |
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| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE) |
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| Target | 5.2 nM (PDE5)[1]. |
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| References | [1]. Sakamoto T, et al. The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5460-5. |
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Chemical & Physical Properties
| Molecular Formula | C23H26ClN7O3 |
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| InChIKey | WEAJZXNPAWBCOA-MRXNPFEDSA-N |
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| SMILES | COc1ccc(CNc2nc(N3CCCC3CO)ncc2C(=O)NCc2ncccn2)cc1Cl |
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