Introduction：Basic information about CAS 1694731-93-5|Propargyl-PEG3-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propargyl-PEG3-CH2COOH |
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| CAS Number | 1694731-93-5 | Molecular Weight | 246.26 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C11H18O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
Propargyl-PEG3-CH2COOH BiologicalActivity
| Description | Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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| References | [1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461. |
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Chemical & Physical Properties
| Molecular Formula | C11H18O6 |
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| Molecular Weight | 246.26 |
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| InChIKey | MJRNNISHHNMYAE-UHFFFAOYSA-N |
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| SMILES | C#CCOCCOCCOCCOCC(=O)O |
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| Storage condition | -20°C |
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