Introduction：Basic information about CAS 251647-54-8|2'-O-MOE-rC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-O-MOE-rC |
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| CAS Number | 251647-54-8 | Molecular Weight | 877.960 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C48H56N5O9P | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite |
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| Synonym | More Synonyms |
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2'-O-MOE-rC BiologicalActivity
| Description | 2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA[1][2]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others |
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| References | [1]. Prakash TP, et al. Comparing in vitro and in vivo activity of 2'-O-[2-(methylamino)-2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides. J Med Chem. 2008 May 8;51(9):2766-76. [2]. Li M, et al. Synthesis and cellular activity of stereochemically-pure 2'-O-(2-methoxyethyl)-phosphorothioate oligonucleotides. Chem Commun (Camb). 2017 Jan 3;53(3):541-544. |
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Chemical & Physical Properties
| Molecular Formula | C48H56N5O9P |
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| Molecular Weight | 877.960 |
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| Exact Mass | 877.381592 |
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| LogP | 10.57 |
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| InChIKey | IAFVTVZPQIFRAU-NXPFYNPLSA-N |
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| SMILES | COCCOC1C(OP(OCCC#N)N(C(C)C)C(C)C)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC1n1ccc(NC(=O)c2ccccc2)nc1=O |
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Safety Information
Synonyms
| N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5-methyl-2'-O-methylcytidine |
| MFCD15145377 |
| Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-methyl-2'-O-methyl- |
