CAS 615258-40-7|Denosumab

Introduction：Basic information about CAS 615258-40-7|Denosumab, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Denosumab BiologicalActivity
3. Chemical & Physical Properties

Common Name	Denosumab
CAS Number	615258-40-7	Molecular Weight	/
Density	/	Boiling Point	/
Molecular Formula	C₆₄₀₄H₉₉₁₂N₁₇₂₄O₂₀₀₄S₅₀	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Denosumab (usan)

Denosumab BiologicalActivity

Description	Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].
Related Catalog	Research Areas >>Cancer
References	[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82. [2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.

Description

Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].

Related Catalog

Research Areas >>Cancer

References

[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82.

[2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.

Chemical & Physical Properties

Molecular Formula	C₆₄₀₄H₉₉₁₂N₁₇₂₄O₂₀₀₄S₅₀

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