Introduction：Basic information about 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE CAS 433-06-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Basic information
| Product Name: | 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE |
| Synonyms: | TRIFLUORETHYLTOSYLATE;TRIFLUOROETHANOL TOSYLATE;P-TOLUENESULFONIC ACID 2,2,2-TRIFLUOROETHYL ESTER;2,2,2-trifluoro-, p-toluenesulfonate;o-(p-tosyl)a,a,a,-trifluoroethanol;2,2,2-Trifluoroethyl 4-methylbenzenesulphonate, 2,2,2-Trifluoroethyl tosylate;2,2,2-Trifluoroethyl toluene-4-sulphonate 98%;2,2,2-Trifluoroethyl p-toluenesulfonate 99% |
| CAS: | 433-06-7 |
| MF: | C9H9F3O3S |
| MW: | 254.23 |
| EINECS: | 207-085-5 |
| Product Categories: | Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;Organic Building Blocks;Sulfur Compounds;Tosylates;API intermediates;blocks;BuildingBlocks;FluoroCompounds |
| Mol File: | 433-06-7.mol |
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2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Chemical Properties
| Melting point | 36-38 °C(lit.) |
| Boiling point | 87-92 °C0.1 mm Hg(lit.) |
| density | 1 g/cm3 |
| Fp | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| form | Solid |
| color | White to Off-White |
| Sensitive | Moisture Sensitive |
| BRN | 2699394 |
| Stability: | Hygroscopic |
| InChI | 1S/C9H9F3O3S/c1-7-2-4-8(5-3-7)16(13,14)15-6-9(10,11)12/h2-5H,6H2,1H3 |
| InChIKey | IGKCQDUYZULGBM-UHFFFAOYSA-N |
| SMILES | Cc1ccc(cc1)S(=O)(=O)OCC(F)(F)F |
| CAS DataBase Reference | 433-06-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate(433-06-7) |
| EPA Substance Registry System | Ethanol, 2,2,2-trifluoro-, 4-methylbenzenesulfonate (433-06-7) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 29049090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Usage And Synthesis
| Chemical Properties | WHITE CRYSTALLINE SOLID |
| Uses | 2,2,2-Trifluoroethyl Tosylate is a trifluoroethylation agent used in the preparation of 2,2,2-trifluoroethyl phenyl sulfone, a potential 2,2,2-trifluoroethyl pronucleophile. |
| Synthesis | 2,2,2-Trifluoroethyl p-Toluenesulfonate is easily prepared by treating 2,2,2-trifluoroethanol with p-Toluenesulfonyl Chloride in pyridine or in aqueous acetone containing NaOH. |
| Precautions | Quite stable; can be handled without any special technique and stored at room temperature; use in a fume hood. |
2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE Preparation Products And Raw materials
| Preparation Products | Benzene, [(2,2,2-trifluoroethoxy)methyl]--->Bicyclo[2.2.1]heptane, 2-(2,2-difluoroethenyl)--->2,2,2-TRIFLUOROETHYL METHYL ETHER-->Ethane, 1,1,1-trifluoro-2-(methylthio)--->Ethanone, 1-[3-(2,2,2-trifluoroethoxy)phenyl]- |
