Introduction：Basic information about 2-Amino-2-methyl-1,3-propanediol CAS 115-69-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-Amino-2-methyl-1,3-propanediol Basic information
| Product Name: | 2-Amino-2-methyl-1,3-propanediol |
| Synonyms: | 1,1-Di(hydroxymethyl)ethylamine;1,3-Dihydroxy-2-methyl-2-propylamine;1,3-Propanediol, 2-amino-2-methyl-;2-amino-2-methyl-3-propanediol;2-Amino-2-methylpropan-1,3-diol;2-Amino-2-methylpropane-1,3-diol;2-Amino-2-methylpropanediol;2-AMINO-2-METHYL-1,3-PROPANEDIOL 98+% |
| CAS: | 115-69-5 |
| MF: | C4H11NO2 |
| MW: | 105.14 |
| EINECS: | 204-100-7 |
| Product Categories: | buffer;API intermediates;Industrial/Fine Chemicals |
| Mol File: | 115-69-5.mol |
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2-Amino-2-methyl-1,3-propanediol Chemical Properties
| Melting point | 100-110 °C (lit.) |
| Boiling point | 151 °C/10 mmHg (lit.) |
| density | 1.0509 (estimate) |
| vapor density | 3.63 (vs air) |
| vapor pressure | ~10 mm Hg ( 152 °C) |
| refractive index | 1.4754 (estimate) |
| Fp | >100°C |
| storage temp. | Store below +30°C. |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Crystalline Powder |
| color | White |
| PH | 10.0-12.0 (20℃, 0.5M in H2O) |
| PH Range | 7.8 - 9.7 |
| pka | 8.8(at 25℃) |
| Water Solubility | 2500 g/L (20 ºC) |
| λmax | λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.03 |
| Merck | 13,447 |
| BRN | 635708 |
| Stability: | Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids. |
| Major Application | diagnostic assay manufacturing |
| Cosmetics Ingredients Functions | BUFFERING |
| Cosmetic Ingredient Review (CIR) | 2-Amino-2-methyl-1,3-propanediol (115-69-5) |
| InChI | 1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3 |
| InChIKey | UXFQFBNBSPQBJW-UHFFFAOYSA-N |
| SMILES | CC(N)(CO)CO |
| LogP | -1.31 at 22℃ |
| CAS DataBase Reference | 115-69-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Amino-2-methyl-1,3-propanediol(115-69-5) |
| EPA Substance Registry System | 1,3-Propanediol, 2-amino-2-methyl- (115-69-5) |
Safety Information
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36-37/39 |
| RIDADR | UN 3259 8/PG 2 |
| WGK Germany | 1 |
| RTECS | TY2975000 |
| F | 3-23 |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29221980 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
| Toxicity | LD50 orally in Rabbit: 17000 mg/kg |
2-Amino-2-methyl-1,3-propanediol Usage And Synthesis
| Chemical Properties | white powder |
| Uses | Emulsifying agent (in soap form) for oils, fats, and waxes; absorbent for acidic gases; organic synthesis; cosmetics. |
| Uses | A useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one. |
| Definition | ChEBI: An aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2. |
| Purification Methods | Crystallise the diol three times from MeOH, dry in a stream of dry N2 at room temperature, then in a vacuum oven at 55o. Store it over CaCl2 [Hetzer & Bates J Phys Chem 66 308 1962]. [Beilstein 4 IV 1881.] |
2-Amino-2-methyl-1,3-propanediol Preparation Products And Raw materials
| Preparation Products | 1,3-Propanediol, 2-methyl-2-[(phenylmethyl)amino]--->Crisnatol-->MFCD24849117 |
