2-Aminobenzotrifluoride CAS 88-17-5
Introduction：Basic information about 2-Aminobenzotrifluoride CAS 88-17-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-Aminobenzotrifluoride Basic information
| Product Name: | 2-Aminobenzotrifluoride |
| Synonyms: | 2-(Trifluoromethyl)aniline,α,α,α-Trifluoro-o-toluidine, 2-Aminobenzotrifluoride;2-Aminobenzotrifluor;2-(Trifluoromethyl)anilinealpha,alpha,alpha-Trifluoro-o-toluidine;2-AMINOBENZOTRIFLUORIDE FOR SYNTHESIS;The three adjacenttrifluoroMethylaniline;2-(TrifluoroMethyl)aniline 99%;2-(TrifluoroMethyl)aniline, 97+%;Neighboring aMino trifluoro toluene |
| CAS: | 88-17-5 |
| MF: | C7H6F3N |
| MW: | 161.12 |
| EINECS: | 201-806-7 |
| Product Categories: | Anilines, Aromatic Amines and Nitro Compounds;Aromatic Halides (substituted);Amines;Building Blocks;C7;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;amine;Pyridines;API intermediates |
| Mol File: | 88-17-5.mol |
2-Aminobenzotrifluoride Chemical Properties
| Melting point | 34 °C(lit.) |
| Boiling point | 170-173 °C(lit.) |
| density | 1.282 g/mL at 25 °C(lit.) |
| vapor pressure | 2.1-12.1hPa at 20-50℃ |
| refractive index | n |
| Fp | 131 °F |
| storage temp. | Store below +30°C. |
| solubility | 4g/l |
| form | Liquid |
| pka | 1.10±0.10(Predicted) |
| color | Clear colorless to light amber |
| Specific Gravity | 1.282 |
| Water Solubility | 4 g/L (20 ºC) |
| BRN | 879494 |
| InChI | 1S/C7H6F3N/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4H,11H2 |
| InChIKey | VBLXCTYLWZJBKA-UHFFFAOYSA-N |
| SMILES | Nc1ccccc1C(F)(F)F |
| LogP | 2.32 at 23℃ and pH7 |
| CAS DataBase Reference | 88-17-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenamine, 2-(trifluoromethyl)-(88-17-5) |
| EPA Substance Registry System | o-(Trifluoromethyl)aniline (88-17-5) |
Safety Information
| Hazard Codes | T,Xi,Xn,F |
| Risk Statements | 10-23/24/25-33-36/37/38-22-20/21/22 |
| Safety Statements | 36/37/39-45-37/39-26-16-36 |
| RIDADR | UN 2942 6.1/PG 3 |
| WGK Germany | 1 |
| RTECS | XU9210000 |
| Hazard Note | Toxic/Irritant |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29214300 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 Skin Sens. 1B STOT RE 2 Oral |
| Chemical Properties | clear colorless to light amber liquid |
| Uses | o-Aminobenzotrifluoride-d2 is a 4-substituted aniline derivative that exerts special hematotoxicity on red blood cells and induce leukocytosis. o-Aminobenzotrifluoride-d2 is a thiohydrazides used as an antibacterial remedy for Chlamydial infection treatment at chronic stages of infections. |
| General Description | A colorless liquid with a fishlike odor. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | 2-Aminobenzotrifluoride is a halogenated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. |
| Health Hazard | TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. |
| Fire Hazard | Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. |
2-Aminobenzotrifluoride Preparation Products And Raw materials
| Raw materials | 2-(TRIFLUOROMETHYL)ACETANILIDE-->2-Amino-5-chlorobenzotrifluoride-->1-Azido-2-(trifluoroMethyl)benzene solution-->Aniline-->4-(Trifluoromethyl)benzamide-->(Trifluoromethyl)trimethylsilane |
| Preparation Products | 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE-->8-(TRIFLUOROMETHYL)QUINOLINE-2-CARBALDEHYDE-->2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE-->sodium 6-amino-4-hydroxy-5-[[2-(trifluoromethyl)phenyl]azo]naphthalene-2-sulphonate-->4-Aminobenzotrifluoride-->ACID RED 337 |
