2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE CAS 90-24-4

Introduction：Basic information about 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE CAS 90-24-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE Basic information

• Product Name: 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE
• Synonyms: 6-HYDROXY-2,4-DIMETHOXYACETOPHENONE;4,6-DIMETHOXY-2-HYDROXYACETOPHENONE;1-(2-HYDROXY-4,6-DIMETHOXYPHENYL)ETHAN-1-ONE;Hydroxy-4',6'-diMethoxyaceto;2'-Hydroxy-4',6'-dimethoxyacetophenone 97%;JR-8967, 2'-Hydroxy-4',6'-dimethoxyacetophenone, 97%;1,4-dichloro-2-[2,5-dichloro-4-(methylthio)phenyl]-5-(methylthio)benzene;1-(2-Hydroxy-4,6-dimethoxyphenyl)ethan-1-on
• CAS: 90-24-4
• MF: C10H12O4
• MW: 196.2
• EINECS: 201-978-3
• Product Categories: Inhibitors;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Aromatic Acetophenones & Derivatives (substituted);C10;Carbonyl Compounds;Ketones
• Mol File: 90-24-4.mol

2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE Chemical Properties

• Melting point: 80-84 °C(lit.)
• Boiling point: 185°C/20mm
• density: 1.172±0.06 g/cm3(Predicted)
• Fp: 185°C/20mm
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Soluble in hot methanol.
• pka: 9.41±0.15(Predicted)
• form: powder to crystal
• color: White to Light yellow to Light orange
• Merck: 14,10067
• BRN: 1285013
• Stability: Stable under recommended storage conditions., Stable Under Recommended Storage C
• InChI: 1S/C10H12O4/c1-6(11)10-8(12)4-7(13-2)5-9(10)14-3/h4-5,12H,1-3H3
• InChIKey: FBUBVLUPUDBFME-UHFFFAOYSA-N
• SMILES: COc1cc(O)c(C(C)=O)c(OC)c1
• LogP: 2.933 (est)
• CAS DataBase Reference: 90-24-4(CAS DataBase Reference)

Safety Information

• Risk Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• HS Code: 29145090
• Storage Class: 11 - Combustible Solids

2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE Usage And Synthesis

Uses

2'-Hydroxy-4',6'-dimethoxyacetophenone is a chemical with potential antibacterial agent effects and urease inhibitory effects as well as synthesis applications.

Uses

1-(2-Hydroxy-4,6-dimethylphenyl)-ethanone was investigated for its properties as an antibacterial agent and urease inhibitory effects.

Definition

ChEBI: Xanthoxylin is a carboxylic ester. It is functionally related to a phloroglucinol.

Preparation

Preparation by reaction of acetonitrile on phloroglucinol dimethyl ether (Hoesch reaction).

Synthesis

Prod.: by regulated (Di)methylation of Phloracetophenone with Dimethylsulfate in weak aqueous alkali.

References

[1] Bulletin of the Korean Chemical Society, 2013, vol. 34, # 12, p. 3782 - 3786
[2] Patent: WO2010/19861, 2010, A1. Location in patent: Page/Page column 38; 50
[3] Patent: EP2112145, 2009, A1. Location in patent: Page/Page column 14-15
[4] Bulletin of the Korean Chemical Society, 2014, vol. 35, # 4, p. 1154 - 1158
[5] Patent: KR2015/49695, 2015, A. Location in patent: Paragraph 0063-0072

2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE Preparation Products And Raw materials

• Raw materials: 3,5-Dimethoxyphenol acetate-->2',4',6'-TRIMETHOXYACETOPHENONE-->2',4',6'-Trihydroxyacetophenone monohydrate-->3,5-Dimethoxyphenol-->Acetyl chloride-->Iodomethane-->Dimethyl sulfate-->Dimethyl carbonate-->Acetic acid-->Acetone
• Preparation Products: 2-Hydroxy-3-iodo-4,6-dimethoxy acetophenone-->Robustaflavone-->Scutellarein 4',7-dimethyl ether-->2',4',6'-TRIMETHOXYACETOPHENONE-->Isolicoflavonol-->5,7-DIMETHOXYFLAVONE-->Pinostrobin-->aciculatin-->5,7-DIMETHOXYISOFLAVONE