Introduction：Basic information about 2'-O-Methylhelichrysetin CAS 123316-64-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2'-O-Methylhelichrysetin Basic information
| Product Name: | 2'-O-Methylhelichrysetin |
| Synonyms: | 2'-O-Methylhelichrysetin;4,4'-Dihydroxy-2',6'-dimethoxychalcone;2-Propen-1-one, 1-(4-hydroxy-2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-;CH625;(2E)-1-(4-Hydroxy-2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
| CAS: | 123316-64-3 |
| MF: | C17H16O5 |
| MW: | 300.30594 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 123316-64-3.mol |
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2'-O-Methylhelichrysetin Chemical Properties
| Melting point | 192-193 °C |
| Boiling point | 556.0±50.0 °C(Predicted) |
| density | 1.279±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 2mg/mL, clear |
| form | powder |
| pka | 7.18±0.25(Predicted) |
| color | white to beige |
Safety Information
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
2'-O-Methylhelichrysetin Usage And Synthesis
| Uses | 4,4'-Dihydroxy-2',6'-dimethoxychalcone is a Chalcones product that can be isolated from the herbs of Alpinia galanga[1]. |
| Definition | ChEBI: 4,4'-Dihydroxy-2',6'-dimethoxychalcone is a member of phenols. |
| Biological Activity | CH625 is a potent and selective competitive inhibitor of CYP4X1 th at decreases tumor burden, increases survival in glioma intracranial and subcutaneous model in rats. CH625 normalizes tumor vasculature in the C6 and GL261 gliomas through tumor-associated macrophages (TAMs) reprograming and inhibition of VEGF and TGF-β production. |
2'-O-Methylhelichrysetin Preparation Products And Raw materials
