4-Chlorostyrene CAS 1073-67-2
Introduction：Basic information about 4-Chlorostyrene CAS 1073-67-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Chlorostyrene Basic information
| Product Name: | 4-Chlorostyrene |
| Synonyms: | CHLOROSTYRENE-4;4-Chlorostyrene, stabilized, 99%;4-CHLOROSTYRENE , STABILIZED WITH 0.1% 4-TERT-BUTYLCATECHOL;4-CHLOROSTYRENE Stabilised with 0.1% 4-tert-butylcatechol;P-CHLOROSTYRENE;p-chloro-styren;Styrene, p-chloro-;styrene,p-chloro- |
| CAS: | 1073-67-2 |
| MF: | C8H7Cl |
| MW: | 138.59 |
| EINECS: | 214-028-8 |
| Product Categories: | Styrenes;Monomers;Polymer Science;Styrene and Functionalized Styrene Monomers;K00001 |
| Mol File: | 1073-67-2.mol |
4-Chlorostyrene Chemical Properties
| Melting point | -16 °C |
| Boiling point | 192 °C(lit.) |
| density | 1.155 g/mL at 25 °C(lit.) |
| vapor pressure | 0.68 mm Hg ( 20 °C) |
| refractive index | n |
| Fp | 140 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 1.155 |
| Water Solubility | Immiscible with water. |
| BRN | 1098859 |
| InChI | 1S/C8H7Cl/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2 |
| InChIKey | KTZVZZJJVJQZHV-UHFFFAOYSA-N |
| SMILES | Clc1ccc(C=C)cc1 |
| CAS DataBase Reference | 1073-67-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-chloro-4-ethenyl-(1073-67-2) |
| EPA Substance Registry System | Benzene, 1-chloro-4-ethenyl- (1073-67-2) |
Safety Information
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38 |
| Safety Statements | 23-24/25-37/39-26-36 |
| RIDADR | 1993 |
| WGK Germany | 3 |
| RTECS | CZ0533000 |
| TSCA | TSCA listed |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29036990 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Aquatic Chronic 2 Skin Irrit. 2 |
| Hazardous Substances Data | 1073-67-2(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 5200 mg/kg |
| Chemical Properties | clear colourless to slightly yellow liquid. The side chain of p-chlorostyrene is a C=C double bond, so its chemical properties are more active. The compound can polymerize slowly at room temperature, and a polymerization inhibitor (stabilizer) can be added for storage. |
| Uses | 4-Chlorostyrene is used in the preparation of new bis(pyrazolyl)borato olefin complexes of copper(I). It is also employed in the investigation of regioselectivity in the cationic Heck reaction of 4-substituted styrenes. Further, it plays an important role in the preparation of 4-[(4-chloro-phenyl)-thioacetyl]-morpholine. |
| Uses | 4-Chlorostyrene was used in the following studies: Study of chemical and biochemical properties of the vinyl group of styrene by the development of structure activity relationships (SAR). Preparation of new bis(pyrazolyl)borato olefin complexes of copper(I). To investigate the regioselectivity in the cationic Heck reaction of 4-substituted styrenes. |
| Preparation | Synthesis of 4-chlorostyrene: carry out catalytic dehydration reaction by 4-chlorophenethylalcohol at 280°C, the used catalyst is a modified aluminum silicate catalyst, and the yield is 80%. |
| Synthesis Reference(s) | p-Chlorostyrene is commercially produced as a monomer from p-chloroethylbenzene by an oxidation technique. It is also produced as a mixture with o-chlorostyrene. Journal of the American Chemical Society, 69, p. 852, 1947 DOI: 10.1021/ja01196a033 Tetrahedron Letters, 31, p. 5061, 1990 DOI: 10.1016/S0040-4039(00)97806-7 |
| General Description | 4-Chlorostyrene is a para-halogenated styrene derivative. It undergoes graft copolymerization with acrylonitrile (AN) onto ethylene-propylene-diene terpolymer (EPDM) in the presence of benzoyl peroxide (initiator). |
4-Chlorostyrene Preparation Products And Raw materials
| Raw materials | 3-Buten-2-one, 4-(4-chlorophenyl)-, (3E)--->2-(4-CHLOROPHENYL)OXIRANE-->1-CHLORO-4-(1,2-DIBROMOETHYL)BENZENE-->4-Chlorocinnamic acid-->4-Chlorobenzyl bromide-->4-Chlorobenzyl chloride-->Benzeneethanesulfonylazide, 4-chloro--->6-Chloroindole-->5H-Cyclopenta[b]pyridine, 4-chloro-6,7-dihydro--->6-CHLORO-2,3-DIHYDRO-1H-INDOLE |
| Preparation Products | 3-[2-chloro-2-(4-chlorophenyl)ethenyl]-2，2-dimethyl cyclopropane carboxylic acid-->4-Chlorophenethylamine-->DIPHENYL(P-VINYLPHENYL)PHOSPHINE-->P-TRIMETHYLSILYL STYRENE-->3-(4-Chlorophenyl)propan-1-ol |
