Adenosine-5'-diphosphate disodium salt CAS 16178-48-6

Introduction：Basic information about Adenosine-5'-diphosphate disodium salt CAS 16178-48-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Adenosine-5'-diphosphate disodium salt Basic information

• Product Name: Adenosine-5'-diphosphate disodium salt
• Synonyms: 5'-ADP-NA2;adenosine5’-(trihydrogendiphosphate),disodiumsalt;Adenosine-5'-diphosphata(ADP),disodium salt;Adenosine-5'-diphosphate disodiuM salt(ADPNa);Adenosine 5 -Diphosphate DisodiuM Salt 5'-ADENYLDIPHOSPHORIC ACID, DISODIUM SALT;ADENOSINE DIPHOSPHATE DINA SALT;ADP DISODIUM
• CAS: 16178-48-6
• MF: C10H15N5O10P2.2Na
• MW: 471.16
• EINECS: 240-314-7
• Product Categories: Pharmaceutical Intermediates;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Nucleotides and their analogs;Nucleic acids;nucleoside;Pharmaceutical
• Mol File: 16178-48-6.mol

Adenosine-5'-diphosphate disodium salt Chemical Properties

• storage temp.: -20°C
• form: Powder
• color: White
• Optical Rotation: [α]20/D 29.6±1°, c = 0.5% in 0.5 M Na2HPO4
• Water Solubility: Soluble in water.
• Sensitive: Hygroscopic
• BRN: 3645656
• InChIKey: AIZARHCNBKWDRW-KWIZKVQNSA-L
• SMILES: [Na+].[Na+].C(OP(=O)(O)OP(O)(O)=O)[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H]([O-])[C@@H]1[O-]
• CAS DataBase Reference: 16178-48-6(CAS DataBase Reference)
• EPA Substance Registry System: Adenosine 5'-(trihydrogen diphosphate), disodium salt (16178-48-6)

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• F: 10-21
• TSCA: TSCA listed
• HS Code: 29349990
• Storage Class: 11 - Combustible Solids

Adenosine-5'-diphosphate disodium salt Usage And Synthesis

Description

Adenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.

Chemical Properties

White crystalline powder

Uses

Adenosine-5'-diphosphate disodium salt is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

Application

Adenosine-5'-diphosphate disodium salt is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels.

Reactions

Adenosine-5'-diphosphate disodium salt can participate in a variety of enzymatic reactions in organisms.

Biochem/physiol Actions

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y1 and P2Y12. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.