Introduction：Basic information about amyrin palmitate CAS 5973-06-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
amyrin palmitate Basic information
| Product Name: | amyrin palmitate |
| Synonyms: | beta-amyrin palmitate;5α-Oleana-12-ene-3β-ol hexadecanoate;Hexadecanoic acid oleana-12-ene-3β-yl ester;Olean-12-en-3β-ol hexadecanoate;Oleana-12-ene-3β-ol palmitate;β-Amyrin 3-palmitate;Balanophorin A;Olean-12-en-3-ol,3-hexadecanoate, (3b)- |
| CAS: | 5973-06-8 |
| MF: | C46H80O2 |
| MW: | 665.14 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 5973-06-8.mol |
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amyrin palmitate Chemical Properties
| Boiling point | 661.4±54.0 °C(Predicted) |
| density | 0.97±0.1 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| LogP | 18.579 (est) |
Safety Information
amyrin palmitate Usage And Synthesis
| Description | Beta-Amyrin palmitate may release norepinephrine from newly synthesized pools, and thus, it may activate noradrenergic activity. Beta-Amyrin palmitate, like mianserin and imipramine, reduces the duration of immobility of mice significantly in a dose-dependent manner (5, 10 and 20 mg kg-1);(1)Beta-Amyrin palmitate or mianserin elicits a dose-related reduction in locomotor activity of mice and antagonizes locomotor stimulation induced by methamphetamine, imipramine increases locomotor activity and potentiates methamphetamine-induced hyperactivity;(2)Beta-Amyrin palmitate shows no effect on reserpine-induced hypothermia, whilst mianserin (10 mg kg-1) and imipramine (10 and 20 mg kg-1) antagonizes the reserpine-induced effect;(3)Beta-amyrin palmitate has similar properties in some respects to mianserin and might possess a sedative action. |
| Uses | β-Amyrin palmitate shows HMG-CoA reductase inhibition[1]. And β-Amyrin palmitate has anti-diabetes mellitus activity[2]. |
| target | LDL | HMG-CoA Reductase | Adrenergic Receptor |
| References | [1] Maurya R, et al. β-Amyrin acetate and β-amyrin palmitate as antidyslipidemic agents from Wrightia tomentosa leaves.?Phytomedicine. 2012;19(8-9):682-685. DOI:10.1016/j.phymed.2012.03.013
[2] Nair SA, et al. Promising anti-diabetes mellitus activity in rats of β-amyrin palmitate isolated from Hemidesmus indicus roots.?Eur J Pharmacol. 2014;734:77-82. DOI:10.1016/j.ejphar.2014.03.050 |
amyrin palmitate Preparation Products And Raw materials
