Bis(di-tert-butyl)-4-dimethylaminophenylphosphine CAS 932710-63-9

Introduction：Basic information about Bis(di-tert-butyl)-4-dimethylaminophenylphosphine CAS 932710-63-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Bis(di-tert-butyl)-4-dimethylaminophenylphosphine Basic information

• Product Name: Bis(di-tert-butyl)-4-dimethylaminophenylphosphine
• Synonyms: Bis(di-tert-butyl)-4-dimethylaminophenylphosphine;[(4-Dimethylaminophenyl)]di(tert-butyl)phosphine;[4-(Dimethylamino)phenyl]bis(tert-butyl)phosphine;4,4'-Phosphinediylbis(2,3-di-tert-butyl-N,N-dimethylaniline);N,N-Dimethyl 4-(di(tert-butyl)phosphino)aniline;95% A-taPhos;(4-(N,N-DiMethylaMino)phenyl)di-tert-butyl phosphine,95% A-taPhos;(4-(N,N-DiMethylaMino)phenyl)di-tert-butyl phosphine,95%
• CAS: 932710-63-9
• MF: C16H28NP
• MW: 265.37
• Product Categories: Achiral Phosphine;Aryl Phosphine
• Mol File: 932710-63-9.mol

Bis(di-tert-butyl)-4-dimethylaminophenylphosphine Chemical Properties

• Melting point: 57-61°C
• Boiling point: 349.1±25.0 °C(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: soluble in Acetone
• pka: 4.73±0.24(Predicted)
• form: crystal
• color: white to light-brown
• InChI: InChI=1S/C16H28NP/c1-15(2,3)18(16(4,5)6)14-11-9-13(10-12-14)17(7)8/h9-12H,1-8H3
• InChIKey: IQTHEAQKKVAXGV-UHFFFAOYSA-N
• SMILES: C1(N(C)C)=CC=C(P(C(C)(C)C)C(C)(C)C)C=C1
• CAS DataBase Reference: 932710-63-9

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/38
• Safety Statements: 26
• WGK Germany: 3
• TSCA: No
• HS Code: 2931499090
• Storage Class: 8B - Non-combustible, corrosive hazardous materials
• Hazard Classifications: Skin Corr. 1B

Bis(di-tert-butyl)-4-dimethylaminophenylphosphine Usage And Synthesis

Use

Bis(di-tert-butyl)-4-dimethylaminophenylphosphine is an organophosphine compound and can be used as an organophosphine ligand.

Reaction

1. Ligand used in a highly-active palladium precatalyst for the efficient amination of aryl chloride.
2. Ligand used in the palladium-catalyzed annulations under microwave enhanced conditions.

Uses

Amphos can be used as an electrophotographic photoreceptor, process cartridge, and image forming electrode.

Uses

Ligand used to prepare a palladium dichloride catalyst (678740) on treatment with PdCl₂(COD). The catalyst effectively cross-couples aryl boronic acids with heteroaryl chlorides.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reagent type: ligand
reaction type: Cross Couplings

References

[1] Patent: CN105237568, 2017, B. Location in patent: Paragraph 0061-0063

Bis(di-tert-butyl)-4-dimethylaminophenylphosphine Preparation Products And Raw materials

• Raw materials: Magnesium, chloro[4-(dimethylamino)phenyl]--->Di-tert-butylphosphine-->4-Bromo-N,N-dimethylaniline-->Hexane-->Di-tert-butylchlorophosphane-->Toluene-->n-Butyllithium
• Preparation Products: Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)