Introduction：Basic information about BOC-GLYCINE METHYL ESTER CAS 31954-27-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
BOC-GLYCINE METHYL ESTER Basic information
| Product Name: | BOC-GLYCINE METHYL ESTER |
| Synonyms: | N-[(1,1-Dimethylethoxy)carbonyl]glycine Methyl Ester;N-(tert-Butoxycarbonyl)glycine Methyl ester, 97%+;BOC-GLYCINE METHYL ESTER;N-(TERT-BUTOXYCARBONYL)GLYCINE METHYL ESTER;Methyl [(tert-butoxycarbonyl)amino]acetate, N-(tert-Butoxycarbonyl)glycine methyl ester;Glycine,N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester;Glycine methyl ester, N-BOC protected 97%;N-(tert-Butoxycarbonyl)glycine methyl ester 97% |
| CAS: | 31954-27-5 |
| MF: | C8H15NO4 |
| MW: | 189.21 |
| EINECS: | |
| Product Categories: | Amino Acid Derivatives;Glycine;Peptide Synthesis;Miscellaneous |
| Mol File: | 31954-27-5.mol |
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BOC-GLYCINE METHYL ESTER Chemical Properties
| Boiling point | 190 °C(lit.) |
| density | 1.28 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.437(lit.) |
| Fp | 109 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Ethyl Acetate |
| pka | 11.06±0.46(Predicted) |
| form | Oil |
| color | Colourless |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C8H15NO4/c1-8(2,3)13-7(11)9-5-6(10)12-4/h5H2,1-4H3,(H,9,11) |
| InChIKey | PHUZOEOLWIHIKH-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)CNC(OC(C)(C)C)=O |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29241990 |
| Storage Class | 10 - Combustible liquids |
BOC-GLYCINE METHYL ESTER Usage And Synthesis
| Chemical Properties | Colorless to yellow liquid |
| Uses | Boc-glycine methyl ester is a amino acid glycine (G615990) derivative, used widely in various synthetic preparations of pharmaceutical goods and antioxidants. N-[(1,1-Dime thylethoxy)carbonyl]glycine Methyl Ester can be used in the preparation of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. |
| Uses | It is used as a pharmaceutical, chemical, paint and dye intermediate. |
| reaction suitability | reaction type: solution phase peptide synthesis |
BOC-GLYCINE METHYL ESTER Preparation Products And Raw materials
| Preparation Products | N-Boc-N-methyl glycine methyl ester-->BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE |
