Bromelain from pineapple stem 2 u/mg CAS 37189-34-7

Introduction:Basic information about Bromelain from pineapple stem 2 u/mg CAS 37189-34-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Bromelain from pineapple stem 2 u/mg Basic information

Product Name:Bromelain from pineapple stem 2 u/mg
Synonyms:Einecs 253-387-5;Bromelain from pineapple stem min. 0.4 DMC-U/mg;ANANAS COMOSUS;BroMelain froM pineapple steM Min. 0.4 DMC-U/Mg powder;Pineapple stem bromelain;Bromelain POS;BROMELAIN FROM PINEAPPLE STEM 2 U/MG;Bromelain from pineapple stem
CAS:37189-34-7
MF:n.a.
MW:0
EINECS:253-387-5
Product Categories:BromelainNutrition Research;ProteaseApplication Index;3.4.x.x Peptidases;3.x.x.x Hydrolases;Biochemicals Found in Plants;Proteases&Protein Sequencing;ProteasesEnzymes, Inhibitors, and Substrates;Proteolytic Enzymes and Substrates;Proteolytic EnzymesEnzyme Class Index;Selective Proteolytic Enzymes;BromelainEnzymes, Inhibitors, and Substrates
Mol File:Mol File

Bromelain from pineapple stem 2 u/mg Chemical Properties

storage temp. -20°C
solubility H2O: soluble1.0mg/mL, clear, colorless
form powder
color yellow-brown
Water Solubility H2O: soluble 1.0mg/mL, clear, colorless
Specific Activity≥3units/mg protein
Cosmetics Ingredients FunctionsKERATOLYTIC
SKIN CONDITIONING

Safety Information

Hazard Codes Xn,Xi
Risk Statements 36/37/38-42
Safety Statements 22-24-26-36/37-36
WGK Germany 1
10-21
HS Code 35079090
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3

Bromelain from pineapple stem 2 u/mg Usage And Synthesis

DescriptionBromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants (Ananas comosus (L.) Merryl). Bromelain is usually found in the fruit and stem, but it is also easy to find in small amounts in the leaf, skin, core, etc. Bromelain from pineapple stem is known as stem bromelain (SBM). SBM has a unique content compared with bromelain from fruit (FBM) because SBM contains many mixtures of various types of thiol-endopeptidases. Based on the research of Heinecke and Gortner, SBM concentrations are better than FBM. Bromelain has been reported to have medical efficacy. Bromelain has been used traditionally to relieve tense muscles, inflammation, and connective tissue. In recent years, bromelain has been used as an anti-inflammatory, antiedematous, and antithrombotic agent (preventing blood clotting). In addition, bromelain showed activity in preventing lung metastases and potentially as an anticancer agent[1].
Chemical PropertiesYellow-brown powder
UsesBromelain may be used to inhibit the biosysnthesis of proinflammatory prostaglandins. It may be used to reduce clotting efficiency. Bromelain, from pineapple stem, has been used to make enzymatic hydrolysates of honeybee-collected pollen .
Biochem/physiol ActionsBromelain is a cysteine endopeptidase with broad specificity for cleavage of proteins. Bromelain may be from a stem or piece of fruit. Product P3169 (pGlu-Phe-Leu-p-nitroanilide) may be used as a chromogenic substrate for the assay of bromelain.
Purification MethodsThis protease has been purified via the acetone powder, G-75 Sephadex gel filtration and Bio-Rex 70 ion-exchange chromatography, and has 1cm 20.1 at 280nm. The protease from pineapple hydrolyses benzoyl glycine ethyl ester with a Km (app) of 210mM and kcat of 0.36 sec-1 . [Murachi Methods Enzymol 19 273 1970, Balls et al. Ind Eng Chem 33 950 1941.]
References[1] Khairunnisa, F. A. et al. “Bromelain content of extract from stem of pineapple (Ananas comosus (L.) Merr).” 2018. 0.

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