Carbazochrome sodium sulfonate CAS 51460-26-5

Introduction：Basic information about Carbazochrome sodium sulfonate CAS 51460-26-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Carbazochrome sodium sulfonate Basic information

• Product Name: Carbazochrome sodium sulfonate
• Synonyms: 1-METHYL-6-OXO-2,3,5,6-TETRAHYDROINDOLE-5-SEMICARBAZONO-2-SULFONIC ACID SODIUM SALT 3 HYDRATE;CARBAZOCHROME SODIUM SULFONATE;CARBAZOCHROME SODIUM SULFONATE TRIHYDRATE;adonatrihydrate;adrenochromesulfonateac17trihydrate;sodium1-methyl-5-semicarbazono-6-oxo-2,3,5,6-tetrahydroindole-3-sulfonate;thyl-6-oxo-,monosodiumsalt,trihydrate;CARBAZOCHROMESODIUMSULPHONATE
• CAS: 51460-26-5
• MF: C10H17N4NaO8S
• MW: 376.32
• EINECS: 257-217-0
• Product Categories: Miscellaneous;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Analgesic series;51460-26-5
• Mol File: 51460-26-5.mol

Carbazochrome sodium sulfonate Chemical Properties

• Melting point: approximate 210℃(dec.)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: DMSO (Sparingly), Methanol (Slightly)
• form: Solid
• color: Yellow to Dark Orange
• PH: pH (16g/l, 25℃) 5.0～6.0
• Stability: Hygroscopic, Moisture Sensitive, Temperature Sensitive
• InChIKey: HLFCZZKCHVSOAP-DAMYXMBDSA-M
• SMILES: C12=C/C(/C(=O)C=C1N(C(S([O-])(=O)=O)C2)C)=N\NC(=O)N.O.O.O.[Na+]
• CAS DataBase Reference: 51460-26-5(CAS DataBase Reference)

Carbazochrome sodium sulfonate Usage And Synthesis

Chemical Properties

Carbazochrome sodium sulfonate is Yellow Solid

Uses

Carbazochrome sodium sulfonate is a Phosphatidylinositol hydrolysis inhibitor in endothelial cells.

Uses

Carbazochrome Sodium Sulfonate Hydrate is a phosphatidylinositol hydrolysis inhibitor in endothelial cells.

Uses

Carbazochrome is an antihemorrhagic for use in the treatment of hemorrhoids.

in vivo

Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats^[2].

• Animal Model: Male Sprague-Dawley rats weighing 180-230 g^[2]
• Dosage: 1, 5 and 10 mg/kg
• Administration: I.v.; injected 30, 60, or 90 min before Ioxaglate injection (4 g I/kg, i.v.).
• Result: Attenuated the Ioxaglate-increased vascular permeability at the dose of 1, 5 and 10 mg/kg in a dose-dependent manner, achieving statistical significance at 5 and 10 mg/kg.