Introduction：Basic information about Chloramine-T trihydrate CAS 7080-50-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Chloramine-T trihydrate Basic information
| Product Name: | Chloramine-T trihydrate |
| Synonyms: | CHLORAMINE T 3-HYDRATE;Chloramine-T trihydrate, ACS, 98.0-103.0%;Chloroamine t trihydrate;Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, trihydrate;chloramine-t trihydrate, acs;CHLORAMINE T REAGENT (ACS);N-Chloro-p-toluenesulfonamide sodium salt, Chloraminum;Chloramine-T trihydrate,97+% |
| CAS: | 7080-50-4 |
| MF: | C7H11ClNNaO3S |
| MW: | 247.67 |
| EINECS: | 615-172-8 |
| Product Categories: | Chlorination;Classes of Metal Compounds;Halogenation;Na (Sodium) Compounds (excluding simple sodium salts);Oxidation;Synthetic Organic Chemistry;Typical Metal Compounds;7080-50-4 |
| Mol File: | 7080-50-4.mol |
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Chloramine-T trihydrate Chemical Properties
| Melting point | 167-170 °C(lit.) |
| density | 1.43 |
| bulk density | 540-680kg/m3 |
| Fp | 92 °C |
| storage temp. | Store at +2°C to +8°C. |
| solubility | H2O: passes test |
| form | Crystalline Powder |
| pka | pK1:4.54(+1) (25°C) |
| color | White to off-white |
| PH | 8-10 (50g/l, H2O, 20℃) |
| Odor | Chlorine like |
| PH Range | 8 - 10 |
| Water Solubility | Soluble in water and ethyl alcohol. Insoluble in benzene and ethers. |
| Sensitive | Moisture Sensitive |
| Merck | 14,2075 |
| BRN | 3924168 |
| InChI | 1S/C7H7ClNO2S.Na.3H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8;;;;/h2-5H,1H3;;3*1H2/q-1;+1;;; |
| InChIKey | NZYOAGBNMCVQIV-UHFFFAOYSA-N |
| SMILES | O.O.O.Cc1ccc(cc1)S(=O)(=O)N([Na])Cl |
| LogP | 2.111 (est) |
| CAS DataBase Reference | 7080-50-4(CAS DataBase Reference) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 22-31-34-42 |
| Safety Statements | 22-26-36/37/39-45-7 |
| RIDADR | UN 3263 8/PG 3 |
| WGK Germany | 2 |
| RTECS | XT5616800 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29350090 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Acute Tox. 4 Oral
Eye Dam. 1
Resp. Sens. 1
Skin Corr. 1B |
| Toxicity | LD50 orally in Rabbit: 935 mg/kg |
Chloramine-T trihydrate Usage And Synthesis
| Chemical Properties | Chloramine T is a white to yellow crystalline powder with characteristic odor. It is an air sensitive and corrosive, cause eye and skin burns and chemical dangers: Chloramine T is known to explode on heating above 130°C (anhydrous). Chloramine T decomposes slowly under the influence of air producing chlorine (trihydrate). On heating or on contact with acids it decomposes and produce toxic gases. |
| Description | Chloramine-T is commercially available in the form of a trihydrate and is a stable white to pale yellow solid. Chloramine T Sodium Salt Trihydrate is a reagent for selective oxidation of methionine. It is used as an antibacterial agent; a topical antiseptic. Capable of oxidative cyclization to produce various heterocycles. Nitrene source for aziridinations and aminohydroxylations. Reactant for Preparation of factor Xa inhibitors as novel anticoagulants. |
| Uses | Chloramine-T trihydrate can be used for detection of bromate and halogens. |
| Uses | Detection of bromate and halogens. Source of halonium ions and nitrogen anions in organic synthesis. |
| Uses | Chloramine-T trihydrate is used as an intermediate in the manufacture of chemical substances such as pharmaceuticals. It combines with iodogen or lactoperoxidase and is commonly used for labeling peptides and proteins with radioiodine isotopes. Hypochlorite released from chloramine-T acts as an effective oxidizing agent for iodide to form iodine monochloride (ICl). |
| General Description | Chloramine T (CAT) trihydrate is a commonly used reagent for organic synthesis especially in heterocyclic chemistry. CAT is an active chlorine compound that shows antimicrobial activity. |
| reaction suitability | reagent type: oxidant |
| Purification Methods | Recrystallise it from hot water (2mL/g). Dry it in a desiccator over CaCl2 where it loses water. Protect it from sunlight. It is used for the detection of bromate and halogens, and Co, Cr, Fe, Hg, Mn, Ni and Sb ions. [Campbell & Johnson Chem Rev 78 65 1978, Bremner Synthetic Reagents 6 9 1985, Chattaway J Chem Soc 87 145 I1905, Inglis J Soc Chem Ind (Lond) 37 288 1918, Beilstein 11 H 107, 11 I 29, 11 II 62, 11 III 300, 2 IV 457.] |
Chloramine-T trihydrate Preparation Products And Raw materials
| Preparation Products | 2-Methoxypyrimidine-5-boronic acid-->1,3,4-Oxadiazol-2-amine,5-(1,1-dimethylethyl)-(9CI) |
