cyclo (Arg-Ala-Asp-d-Phe-Lys) CAS 756500-23-9

Introduction：Basic information about cyclo (Arg-Ala-Asp-d-Phe-Lys) CAS 756500-23-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

cyclo (Arg-Ala-Asp-d-Phe-Lys) Basic information

• Product Name: cyclo (Arg-Ala-Asp-d-Phe-Lys)
• Synonyms: cyclo (Arg-Ala-Asp-d-Phe-Lys);c(RADfK);Cyclo(-Arg-Ala-Asp-D-Phe-Lys) trifluoroacetate salt;CYCLO(RADFK), BR;Cyclo(RADfK),c(RADfK), BR;Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl);2-((2S,5R,8S,11S,14S)-8-(4-aminobutyl)-5-benzyl-11-(3-guanidinopropyl)-14-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)aceticacid;Cyclo(RADfK),Inhibitor,inhibit,Integrin
• CAS: 756500-23-9
• MF: C28H43N9O7
• MW: 617.71
• Mol File: 756500-23-9.mol

cyclo (Arg-Ala-Asp-d-Phe-Lys) Chemical Properties

• density: 1.45±0.1 g/cm3(Predicted)
• storage temp.: Store at -20°C
• form: Solid
• pka: 4.01±0.10(Predicted)
• color: White to off-white
• Water Solubility: Water : ≥ 25 mg/mL (40.47 mM)
• Sequence: Cyclo(Arg-Ala-Asp-d-Phe-Lys)
• InChIKey: SMFHXHGBDFBWOX-OVACWLFONA-N
• SMILES: C(C1C=CC=CC=1)[C@H]1NC([C@@]([H])(NC([C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC1=O)C)=O)CC(=O)O)=O |&1:7,10,14,18,29,r|

cyclo (Arg-Ala-Asp-d-Phe-Lys) Usage And Synthesis

Uses

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

References

[1] Srivatsan A, et al. Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics withenhanced tumor-imaging and photosensitizing (PDT) efficacy. Mol Pharm. 2011 Aug 1;8(4):1186-1197. DOI:10.1021/mp200018y