Introduction：Basic information about DL-Leucine CAS 328-39-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
DL-Leucine Basic information
| Product Name: | DL-Leucine |
| Synonyms: | (R,S)-2-Amino-4-methyl-pentanoicacid;2-Amino-4-methylvalericacid;Leucine, DL-;A-AMINO-ISO-CAPROIC ACID;leucine,dl;(+/-)-2-Amino-4-methylpentanoic acid~H-DL-Leu-OH;DL-LEUCINE, 99+%;DL-LEUCINE BIOSYNTH |
| CAS: | 328-39-2 |
| MF: | C6H13NO2 |
| MW: | 131.17 |
| EINECS: | 206-328-2 |
| Product Categories: | Leucine [Leu, L];alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;Amino Acid Derivatives;amino acid |
| Mol File: | 328-39-2.mol |
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DL-Leucine Chemical Properties
| Melting point | 293-296 °C (subl.) (lit.) |
| alpha | [α]D20 -3.0～+3.0゜ (c=4, HCl) |
| Boiling point | 225.8±23.0 °C(Predicted) |
| density | 1,293 g/cm3 |
| refractive index | 1.4630 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 1 M HCl: soluble |
| pka | pKa: 9.744(25°C) |
| form | Fine Crystalline Powder |
| color | White |
| Odor | wh. sm. cryst. or cryst. powd., odorless, sl. bitter taste |
| Water Solubility | soluble |
| Merck | 14,5451 |
| BRN | 636005 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Major Application | detection
peptide synthesis |
| InChI | 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9) |
| InChIKey | ROHFNLRQFUQHCH-UHFFFAOYSA-N |
| SMILES | CC(C)CC(N)C(O)=O |
| LogP | 0.799 (est) |
| CAS DataBase Reference | 328-39-2(CAS DataBase Reference) |
| NIST Chemistry Reference | DL-Leucine(328-39-2) |
| EPA Substance Registry System | Leucine (328-39-2) |
Safety Information
| Hazard Codes | Xn |
| Safety Statements | 22-24/25-36 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 29224995 |
| Storage Class | 11 - Combustible Solids |
DL-Leucine Usage And Synthesis
| Chemical Properties | White crystalline powder |
| Uses | DL-Leucine is a racemic mixture of the D- and L- enantiomers of Leucine. DL-Leucine is used to form benzimidazole and pyrimidine hydroxy azo dyes with various transition metals. DL-Leucine may be used for the evaluation of chiral amino acid separation techniques.
DL-Leucine is used for the following applications:
- Used as a standard for the measurement of free amino acids
- Used in the process of tritiated leucine uptake
- Used in solution preparation (various organics were used in different combinations and concentrations to model complex surface tension effects, DL-Leucine is one of them). It is chosen due to its presence in atmospheric aerosols and ice nucleation activity as well as for its surfactant character
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| Definition | ChEBI: A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group. |
DL-Leucine Preparation Products And Raw materials
| Raw materials | Carbon dioxide-->SODIUM HYPOBROMITE-->alfa-Bromoisovalericacid |
| Preparation Products | D-2-Amino-4-methylpentanoic acid-->AMMONIUM CARBAMATE-->3-Methylbutanenitrile-->N-(2,4-dinitrophenyl)-DL-leucine-->1-Butanimine, 3-methyl--->N-FORMYL-DL-LEUCINE-->Albutoin-->Leucine, N-(2-methylbenzoyl)--->4-isobutyloxazolidine-2,5-dione |
