Forchlorfenuron CAS 68157-60-8
Introduction：Basic information about Forchlorfenuron CAS 68157-60-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Forchlorfenuron Basic information
| Product Name: | Forchlorfenuron |
| Synonyms: | CPPU;KT-30;FORCHLORFENURON;4-CPPU;1-(2-CHLORO-4-PYRIDYL)-3-PHENYLUREA;1-(2-CHLOROPYRIDIN-4-YL)-3-PHENYL-UREA;4pu30;cn11-3138 |
| CAS: | 68157-60-8 |
| MF: | C12H10ClN3O |
| MW: | 247.68 |
| EINECS: | 614-346-0 |
| Product Categories: | plantgrowth;Agro-Products;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Biochemistry;Chloropyridines;Cytokinins;Halopyridines;Plant Growth Regulators;Plant Hormones;PLANT GROWTH REGULATOR;FINE Chemical & INTERMEDIATES |
| Mol File: | 68157-60-8.mol |
Forchlorfenuron Chemical Properties
| Melting point | 170-172°C |
| Boiling point | 308.4±27.0 °C(Predicted) |
| density | 1.415±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in DMSO or Ethanol |
| pka | 12.55±0.70(Predicted) |
| form | Solid |
| color | White or off-white |
| Stability: | Stable for 1 year from date ofpurchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| Major Application | agriculture environmental |
| InChI | InChI=1S/C12H10ClN3O/c13-11-8-10(6-7-14-11)16-12(17)15-9-4-2-1-3-5-9/h1-8H,(H2,14,15,16,17) |
| InChIKey | GPXLRLUVLMHHIK-UHFFFAOYSA-N |
| SMILES | N(C1C=CN=C(Cl)C=1)C(NC1=CC=CC=C1)=O |
| CAS DataBase Reference | 68157-60-8(CAS DataBase Reference) |
| EPA Substance Registry System | Forchlorfenuron (68157-60-8) |
Safety Information
| Hazard Codes | Xi,N,Xn |
| Risk Statements | 36/37-51/53-40 |
| Safety Statements | 26-36-61-46-36/37 |
| RIDADR | UN3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | YS7182500 |
| HazardClass | 9 |
| PackingGroup | III |
| HS Code | 29333990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 2 Carc. 2 |
| Hazardous Substances Data | 68157-60-8(Hazardous Substances Data) |
| Toxicity | LD50 oral in mouse: > 500mg/kg |
| Description | Forchlorfenuron (68157-60-8) reversibly perturbs mammalian septin assembly, organization and function.? Has no effect on actin or tubulin polymerization.1,2 FCF induces effects on mitosis and migration which phenocopy the effects induced by septin depletion using siRNA.1 A useful tool for exploring the physiological role of septin and its complexes.3,4 |
| Chemical Properties | White Solid |
| Chemical Properties | White to faint yellow crystalline powder. |
| Uses | Forchlorfenuronis is a diphenylurea-derivative cytokinin. Forchlorfenuronis is used as a plant growth regulator (PGR). Forchlorfenuronis is commonly used in horticulture to stimulate the growth of kiwi fruit and grapes. |
| Definition | ChEBI: Forchlorfenuron is a member of the class of phenylureas that is urea substituted by a phenyl group and a 2-chloropyridin-4-yl group at positions 1 and 3 respectively. It is a plant growth regulator widely used in agriculture for improving fruit quality and fruit size. It has a role as a plant growth regulator. It is a member of phenylureas and a monochloropyridine. |
| Agricultural Uses | Plant growth regulator: Forchlorfenuron is as a plant growth regulator to promote cell division, and to improve the quality and theyield of fruits, especially table grapes, grape raisins, andkiwi fruit. In some parts of California, forchlorfenuron issaid to double the size of Thompson seedless grapes anddelay crop maturity up to several weeks.widely used in agriculture on fruits to increase their size, |
| Trade name | CN-11-3183; KT-30®; SKW 20010 |
| Potential Exposure | Phenylurea/substituted urea plantgrowth regulator widely used in agriculture on fruits toincrease their size, to promote cell division, and to improvethe quality and the yield of fruits, especially table grapes,grape raisins, and kiwi fruit. In some parts of California,forchlorfenuron is reputed to double the size of Thompsonseedless grapes and delay crop maturity up to severalweeks. |
| Shipping | UN2767 Phenyl urea pesticides, solid, toxic,Hazard Class: 6.1; Labels: 6.1-Poisonous materials. |
| Incompatibilities | May react with strong oxidizers such aschlorates, peroxides, nitrates, etc. Dust may form explosivemixture with air. |
| Waste Disposal | Containers must be disposedof properly by following package label directions or bycontacting your local or federal environmental controlagency, or by contacting your regional EPA office. If thismaterial cannot be disposed of according to label instruc tions, it may be dissolved or mixed with a combustible sol vent and burned in a chemical incinerator equipped with anafterburner and scrubber. In accordance with 40CFR165,follow recommendations for the disposal of pesticides andpesticide containers. |
| References | [1] QICONG HU Elias T S W James Nelson. Forchlorfenuron alters mammalian septin assembly, organization, and dynamics.[J]. The Journal of Biological Chemistry, 2008: 29563-29571. DOI:10.1074/jbc.m804962200 [2] BRADLEY S. DEMAY. Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton†[J]. Cytoskeleton, 2010, 67 6: 383-399. DOI:10.1002/cm.20452 [3] ANITA A WASIK. Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.[J]. Molecular Biology of the Cell, 2012, 23 17: 3370-3379. DOI:10.1091/mbc.e11-12-1010 [4] DIKLA VARDI-OKNIN Nicola J M Maya Golan. Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1.[J]. PLoS ONE, 2013: e73179. DOI:10.1371/journal.pone.0073179 |
Forchlorfenuron Preparation Products And Raw materials
| Raw materials | Sodium azide-->PHOSGENE-->2-Chloropyridine-->Phenyl isocyanate-->Isonicotinic acid-->2-Chloro-4-nitropyridine 1-oxide-->4-Amino-2-chloropyridine-->2-Chloropyridine-N-oxide-->2-Chloropyridine-4-carbonyl chloride-->Nicotinamide-N-oxide-->Isonicotinamide-->2-CHLOROISONICOTINAMIDE |
