Introduction：Basic information about Gatifloxacin hydrochloride CAS 160738-57-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Gatifloxacin hydrochloride Basic information
| Product Name: | Gatifloxacin hydrochloride |
| Synonyms: | Gatifloxacin base;4-dihydroquinoline-3-carboxylic acid;GatifloxacineHCL;1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylicac;1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)- 4-oxo-1,4-dihydro-quinoline-3-carboxylic acid hydrochloride;gatifloxacin hydrochloride;GATIFLOXACIN LACTATE;Gatifloxacin acid ester |
| CAS: | 160738-57-8 |
| MF: | C22H28FN3O7 |
| MW: | 465.47 |
| EINECS: | 1308068-626-2 |
| Product Categories: | API |
| Mol File: | 160738-57-8.mol |
|
Gatifloxacin hydrochloride Chemical Properties
| Melting point | 162 C |
| InChIKey | CFPJUGZAXVMNBA-UHFFFAOYSA-N |
| SMILES | N1(C=C(C(O)=O)C(=O)C2C=C(F)C(N3CCNC(C)C3)=C(OC)C1=2)C1CC1.C(O)(C(C)O)=O |
| CAS DataBase Reference | 160738-57-8(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-27-36/37/39 |
| HS Code | 29419000 |
Gatifloxacin hydrochloride Usage And Synthesis
| Description | Gatifloxacin is a novel orally-active fluoroquinolone antibiotic with apotent and broad spectrum of activity against gram-positive (S.pneumonia,S.aureus) and gram-negative bacteria. It shows good activity against strainsresistant to established antituberculosis agents. Gatifloxacin was marketed for the treatment of respiratory tract and urinary infections, particularly the treatmentof certain community-acquired infections (such as bronchitis, pneumonia andcommon sexually-transmitted diseases). Comparative studies with ciprofloxacin,ofloxacin and sparfloxacin against fluoroquinolone-resistant organisms indicateda better or equivalent effectiveness with less phototoxic adverse effects. |
| Chemical Properties | pale yellow prisms |
| Originator | Kyori (Japan) |
| Brand name | Tequin |
Gatifloxacin hydrochloride Preparation Products And Raw materials
| Raw materials | 2,4,5-TRIFLUORO-3-METHOXYBENZOIC ACID |
