Introduction:Basic information about Gatifloxacin sesquihydrate CAS 180200-66-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Gatifloxacin sesquihydrate Basic information
| Product Name: | Gatifloxacin sesquihydrate |
| Synonyms: | Gatifloxacin formic acid ethyl ester;Gatifloxacin (300 mg);Gatifloxacin Monohydrate;Gatifloxcin 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-, hydrate (2:3);(+-)-1-C;1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;1-Cyclopropyl-6-fluoro-8-Methoxy-7-(3-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid sesquihydrate |
| CAS: | 180200-66-2 |
| MF: | C19H24FN3O5 |
| MW: | 393.42 |
| EINECS: | 672-577-2 |
| Product Categories: | Active Pharmaceutical Ingredients;APIs |
| Mol File: | 180200-66-2.mol |
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Gatifloxacin sesquihydrate Chemical Properties
| Boiling point | 684℃ |
| RTECS | VB1983600 |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Soluble in 1N NaOH at 10mg/ml |
| form | powder |
| color | white to beige |
| BRN | 14390028 |
| InChI | InChI=1S/C19H22FN3O4.H2O/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26;/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26);1H2 |
| InChIKey | IJOOSVJZBQQMBV-UHFFFAOYSA-N |
| SMILES | O(C1C(N2CCNC(C)C2)=C(F)C=C2C(=O)C(C(=O)O)=CN(C3CC3)C=12)C.O |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 36/37 |
| WGK Germany | 1 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
Gatifloxacin sesquihydrate Usage And Synthesis
| Uses | Antibacterial. |
| Uses | A broad spectrum antibiotic |
| Brand name | Tequin (Bristol-Myers Squibb); Zymar (Allergan). |
| Biological Activity | Gatifloxacin sesquihydrateis an oral fluoroquinolone broad spectrum antibiotic, inhibitor of bacterial enzymes DNA gyrase and topoisomerase IV, with improved gram-positive and anaerobe coverage. Gatifloxacin is reported to be useful to tre at ocular infection and does not appear to cause phototoxic effects. |
Gatifloxacin sesquihydrate Preparation Products And Raw materials