Introduction:Basic information about N-(m-PEG4)-N'-(amino-PEG3)-Cy5 CAS 2107272-96-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Basic information
| Product Name: | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 |
| Synonyms: | N-(m-PEG4)-N'-(amino-PEG3)-Cy5;N-(m-PEG4)-N'-(amino-PEG3)-Cy5 TFA salt |
| CAS: | 2107272-96-6 |
| MF: | C42H62ClN3O7 |
| MW: | 756.42 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 2107272-96-6.mol |
|
N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Chemical Properties
| solubility | Soluble in Water, DMSO, DMF, DCM |
Safety Information
N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Usage And Synthesis
| Description | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 TFA salt is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free amine group, which will be reactive with cabroxylic acid, activated NHS ester, carbonyl (ketone, aldehyde) etc. The hydophilic PEG spacer increases solubility in aqueous media. |
| Uses | N-(m-PEG4)-N'-(amino-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| IC 50 | PEGs |
| References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Preparation Products And Raw materials