N-(m-PEG4)-N'-(amino-PEG3)-Cy5 CAS 2107272-96-6

Introduction:Basic information about N-(m-PEG4)-N'-(amino-PEG3)-Cy5 CAS 2107272-96-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Basic information

Product Name:N-(m-PEG4)-N'-(amino-PEG3)-Cy5
Synonyms:N-(m-PEG4)-N'-(amino-PEG3)-Cy5;N-(m-PEG4)-N'-(amino-PEG3)-Cy5 TFA salt
CAS:2107272-96-6
MF:C42H62ClN3O7
MW:756.42
EINECS:
Product Categories:
Mol File:2107272-96-6.mol

N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Chemical Properties

solubility Soluble in Water, DMSO, DMF, DCM

Safety Information

N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Usage And Synthesis

DescriptionN-(m-PEG4)-N'-(amino-PEG3)-Cy5 TFA salt is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free amine group, which will be reactive with cabroxylic acid, activated NHS ester, carbonyl (ketone, aldehyde) etc. The hydophilic PEG spacer increases solubility in aqueous media.
UsesN-(m-PEG4)-N'-(amino-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Preparation Products And Raw materials

N-(m-PEG4)-3,3-Dimethyl-3H-indole-N'-(acid-PEG3)-Benzothiazole Cy5 CAS 2107273-86-7
N-(m-PEG4)-N'-(azide-PEG4)-Cy7 CAS 2107273-40-3
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