Introduction：Basic information about N-(m-PEG4)-N'-(PEG4-acid)-Cy5 CAS 2107273-32-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-(m-PEG4)-N'-(PEG4-acid)-Cy5 Basic information
| Product Name: | N-(m-PEG4)-N'-(PEG4-acid)-Cy5 |
| Synonyms: | N-(m-PEG4)-N'-(PEG4-acid)-Cy5;VUN 00829 |
| CAS: | 2107273-32-3 |
| MF: | C45H65ClN2O10 |
| MW: | 829.47 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 2107273-32-3.mol |
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N-(m-PEG4)-N'-(PEG4-acid)-Cy5 Chemical Properties
| solubility | Soluble in Water, DMSO, DMF, DCM |
Safety Information
N-(m-PEG4)-N'-(PEG4-acid)-Cy5 Usage And Synthesis
| Description | N-(m-PEG4)-N'-(PEG4-acid)-Cy5 is a near infrared (NIR) fluorescent Cy 5 labeled PEG linker containing free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media. Cy5 labeled PEG linker can be easily traced from its blue color and strong fluorescence. |
| Uses | N-(m-PEG4)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| IC 50 | PEGs |
| References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
N-(m-PEG4)-N'-(PEG4-acid)-Cy5 Preparation Products And Raw materials
