N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluorobora

Introduction：Basic information about N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluorobora, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Basic information

• Product Name: N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate
• Synonyms: O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN- 3-YL)-N,N,;O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium tetra;O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIZIN-3-YL)-N,N,N',N'-TETRAMETHYLURONIUMTETRAFLUOROBORATE;TDBTU N,N,N'',N''-TETRAMETHYL-O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL) URONIUMTETRAFLUOROBORATE;N,N,N'',N''-TETRAMETHYL-O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL)URONIUM TETRAFLUOROBORATE(TDBTU);2-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE;2-(3,4-DIHYDRO-4-OXO-BENZOTRIAZIN-3-YL)TETRAMETHYLURONIUM TETRAFLUOROBORATE;dihydrooxobenzotriazinyl tetramethyluronium fluoroborate
• CAS: 125700-69-8
• MF: C12H16BF4N5O2
• MW: 349.09
• Product Categories: Peptide;Peptide Coupling Reagents;Coupling Reagent
• Mol File: 125700-69-8.mol

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Chemical Properties

• Melting point: 147 °C (dec.)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: acetonitrile: 0.1 g/mL, clear
• form: Powder or Solid
• color: White to yellow
• Sensitive: Moisture & Light Sensitive
• InChI: InChI=1S/C12H16N5O2.BF4/c1-15(2)12(16(3)4)19-17-11(18)9-7-5-6-8-10(9)13-14-17;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
• InChIKey: FOBCPCIJLQTYBT-UHFFFAOYSA-N
• SMILES: C12C=CC=CC=1N=NN(O/C(=[N+](/C)\C)/N(C)C)C2=O.[B-](F)(F)(F)F
• CAS DataBase Reference: 125700-69-8(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xi
• Risk Statements: 37-36/37/38
• Safety Statements: 22-24/25-36-26
• RIDADR: UN 1759 8/PG III
• WGK Germany: 3
• F: 8-10-21
• HazardClass: 8
• PackingGroup: III
• HS Code: 29339900

N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate Usage And Synthesis

Chemical Properties

Beige crystalline

Uses

O-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate (2-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate, TBTU) may be used as coupling reagent in the synthesis of macrocyclic polyamine derivatives with various length of linkers, condensation reagent in the large-scale preparation of the hematoregulatory nonapeptide (Glp-Glu-Asp)2-DAS-(Lys)2 (2,SK&F 107647), coupling reagent for peptide synthesis which best suppresses racemization during fragment condensation.