N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate CAS 265651-18-1

Introduction：Basic information about N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate CAS 265651-18-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate Basic information

• Product Name: N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate
• Synonyms: 2-SUCCINIMIDO-1,1,3,3-TETRAMETHYLURONIM HEXAFLUOROPHOSPHATE;2-SUCCINIMIDO-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE;HSTU;O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium hexafluorophosphate;O-(N-SUCCINIMIDYL)-N,N,N',N'-TETRA-;O-(N-Succinimidyl)-N,N,N',N'-tetramethyluroniumhe;o-(n-succinimidyl)-n,n,n',n'-tetra-methyluroniumpf6;HSTU O-(N-SUCCINIMIDYL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
• CAS: 265651-18-1
• MF: C9H16F6N3O3P
• MW: 359.21
• Product Categories: Coupling Reagent
• Mol File: 265651-18-1.mol

N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate Chemical Properties

• Melting point: 218-221°C
• storage temp.: -20°C
• solubility: Soluble in acetonitrile 0.5 g/mL.
• form: Powder or Crystalline Powder
• color: White to off-white
• Sensitive: Moisture Sensitive
• Major Application: peptide synthesis
• InChI: InChI=1S/C9H16N3O3.F6P/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;1-7(2,3,4,5)6/h5-6H2,1-4H3;/q+1;-1
• InChIKey: STWZCCVNXFLDDD-UHFFFAOYSA-N
• SMILES: [P+5]([F-])([F-])([F-])([F-])([F-])[F-].O(N1C(CCC1=O)=O)/C(=[N+](\C)/C)/N(C)C
• CAS DataBase Reference: 265651-18-1(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-60-37
• WGK Germany: 3
• HS Code: 29280000
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate Usage And Synthesis

Chemical Properties

White to off-white crystalline powder

Uses

Coupling reagent for peptide synthesis and the formation of other amides. Yield in aqueous solution is excellent too.

Uses

Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.

General Description

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate can be used to prepare N-succinimidyl 4-[¹⁸F]fluorobenzoate ([¹⁸F]-SFB), a prosthetic group for the fluorination of biomolecules for PET imaging.

reaction suitability

reaction type: Coupling Reactions