Introduction：Basic information about Oxibendazole CAS 20559-55-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Oxibendazole Basic information
| Product Name: | Oxibendazole |
| Synonyms: | N-(6-propoxy-1H-benzimidazol-2-yl)-carbamic acid methyl ester;oxibendazole Solution, 100ppm;5-Propoxy-2-(carbomethoxyamino)benzimidazole;Methyl (5-n-propoxy-2-benzimidazolyl)carbamate;Methyl 5-propoxybenzimidazole-2-carbamate;5-Propoxy-1H-benzimidazole-2-carbamic acid methyl ester;(5-Pmpoxy-1H- benzimidazol-2-y1)carbamic acid methyl ester;Methyl N-(5-propoxy-3H-benzoiMidazol-2-yl)carbaMate |
| CAS: | 20559-55-1 |
| MF: | C12H15N3O3 |
| MW: | 249.27 |
| EINECS: | 243-877-7 |
| Product Categories: | Various Metabolites and Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Active Pharmaceutical Ingredients;Inhibitors |
| Mol File: | 20559-55-1.mol |
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Oxibendazole Chemical Properties
| Melting point | 230-231°C |
| density | 1.301±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly, Heated), THF (Slightly, Heated) |
| pka | 10.60±0.10(Predicted) |
| form | Solid |
| color | Off-White |
| Merck | 14,6936 |
| InChI | 1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16) |
| InChIKey | RAOCRURYZCVHMG-UHFFFAOYSA-N |
| SMILES | CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1 |
| CAS DataBase Reference | 20559-55-1(CAS DataBase Reference) |
Safety Information
| WGK Germany | 3 |
| RTECS | FD0835000 |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | mouse,LDLo,oral,32gm/kg (32000mg/kg),American Journal of Veterinary Research. Vol. 38, Pg. 809, 1977. |
Oxibendazole Usage And Synthesis
| Chemical Properties | Crystalline Solid |
| Uses | alcohol and narcotic antagonist |
| Uses | Anthelmintic. |
| Definition | ChEBI: N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester is a member of benzimidazoles and a carbamate ester. |
| Brand name | Anthelcide EQ (SmithKline Beecham Animal Health); Filaribits Plus (SmithKline Beecham Animal Health). |
| Biochem/physiol Actions | Anthelminthic |
| Veterinary Drugs and Treatments | Oxibendazole is indicated (labeled) for the removal of the followingparasites in horses: large roundworms (Parascaris equorum), largestrongyles (S. edentatus, S. equinus, S. vulgaris), small strongyles,threadworms, and pinworms (Oxyuris equi).
Oxibendazole has also been used in cattle, sheep, and swine; seeDosage section for more information. |
Oxibendazole Preparation Products And Raw materials
| Raw materials | Stannous chloride-->1-Bromopropane-->Methyl chloroformate-->Acetaminophen-->N-METHYLTHIOUREA-->2-Aminobenzimidazole |
